The application of traditional Chinese medicine in preventing disease progression:Past,present and future of“Ji Bing Fang Bian”theoryOA
In the early stages of various diseases—such as COVID-19,influenza,dengue fever,diabetes,pulmonary hypertension and inflammation-driven disorders—failure to intervene promptly can trigger uncontrolled inflammatory responses and multi-system dysfunction,initiating complex pathological cascades that substantially increase morbidity,complication burden,and risk of adverse outcomes.The traditional Chinese medicine(TCM)principle of“preventing disease progression after onset”(Ji Bing Fang Bian)emphasizes early therapeutic intervention to halt disease exacerbation and prevent severe complications.This concept aligns closely with the modern medical strategy of early intervention.This review adopts the TCM theoretical framework of“Ji Bing Fang Bian”to systematically delineate the dynamic progression patterns and key pathophysiological mechanisms underlying the aforementioned conditions.Furthermore,it highlights the unique advantages and clinical value of TCM interventions,which leverage multi-component,multi-target,and multi-pathway synergistic actions to effectively interrupt disease progression.By elucidating the contemporary scientific underpinnings of the“Ji Bing Fang Bian”paradigm,this work aims to provide evidence-informed,and future prospective for the early prevention of these diseases using TCM.
Yuan Long;Cong-Mei Zhang;Hong-Yu Deng;Zi-Ning Peng;Fa-Li Zha;Qian-Qian Wan;Fei-Tian Min;Ning Wang;Zhong-Yu Peng;Huan-Tian Cui;Wei-Bo Wen;Tao Chen
First School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaSchool of Chinese Materia Medica,Yunnan University of Chinese Medicine,Kunming 650500,China Yunnan Key Laboratory of Dai and Yi Medicines,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,China Yunnan Key Laboratory of Dai and Yi Medicines,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,ChinaFirst School of Clinical Medicine/Yunnan Provincial Hospital of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,China
医药卫生
“Ji Bing Fang Bian”theorytraditional Chinese medicinedisease managementbasic studyclinical application
《Traditional Medicine Research》 2026 (12)
P.67-86,20
supported by National Natural Science Foundation of China(No.82505244)Yunnan Fundamental Research Projects(No.202501AT070338)Yunnan"Xingdian Talent Support Program"for Young Talents(No.XDYC-QNRC-2024-518)Young Talent Cultivation Program of China Association of Chinese Medicine(No.2025-QNRC2-B46)TCM Collaborative Special Project–Key Project(No.202501AZ070001-001)Key Clinical Specialty of Traditional Chinese Medicine(Orthopedics),Yunnan Province,Grant No.Yun Cai She[2026]No.1Open Research Fund Program of Yunnan Key Laboratory for Dai and Yi Medicines(Yunnan University of Chinese Medicine)(No.2025ZD2502,2025SS2514).
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