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基于"因加而发"和"既病防变"理论探讨卒中后认知障碍的防治OA

Discussion on the Prevention and Treatment of Post-stroke Cognitive Impairment Based on the Theories of "Onset Due to Accumulated Pathogenic Factors" and "Preventing Disease Progression"

中文摘要英文摘要

基于"因加而发"和"既病防变"理论探讨卒中后认知障碍的防治思路.该病病机属本虚标实,以脏腑虚损为本,新邪引动宿邪为标,正邪交争导致神机失用.基于"因加而发"理论,该病的发生发展与内外邪气交互致病、正虚邪盛动态演变密切相关."既病防变"理论强调分阶段干预:急性期涤痰逐瘀以截断病势,恢复期补肾填精以稳固根基,后遗症期攻补兼施以防传变.此分期论治策略可为延缓卒中后认知障碍进展提供参考.

Based on the theories of "onset due to accumulated pathogenic factors"and"preventing Disease progression",this paper explores the prevention and management strategies for post-stroke cognitive impairment(PSCI).The pathogenesis of PSCI is fundamentally characterized as deficiency in root while excess in manifestation:visceral insufficiency acts as the root cause,while latent pathogens triggered by newly invading pathogenic factors act as the manifestation.The struggle between healthy Qi and pathogenic factors eventually leads to dysfunction of mental spirit.Based on the theory of "onset due to accumulated pathogenic factors",PSCI is related to combined internal and external pathogenic factors,alongside the dynamic evolution of deficient Qi and excessive pathogens.The theory of "preventing disease progression" emphases staged intervention strategies:resolving phlegm and removing blood stasis in the acute phase to halt disease aggravation;tonifying the kidney and replenishing essence during the convalescent phase to consolidate the body's foundation;and applying concurrent purgative and tonifying therapy in the sequela phase to prevent pathological progression and deterioration.This staged therapeutic strategies can offer a reference for postponing the progression of PSCI.

巫欣明;黄安闻;高丽丽

福建中医药大学附属第二人民医院,福建 福州 350003福建中医药大学附属第二人民医院,福建 福州 350003福建中医药大学附属第二人民医院,福建 福州 350003

医药卫生

卒中后认知障碍因加而发既病防变病因病机防治

post-stroke cognitive impairmentonset due to accumulated pathogenic factorspreventing disease progressionetiology and pathogenesisprevention and treatment

《中医研究》 2026 (7)

1-5,5

2024年度福建省自然科学基金联合资助项目(2024J01733)

10.3969/j.issn.1001-6910.2026.07.01

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