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乳腺癌患者经济毒性现状的Meta分析OA

A Meta-analysis of the current status of financial toxicity in breast cancer patients

中文摘要英文摘要

目的 系统评价乳腺癌患者经济毒性的发生现状.方法 检索Embase、PubMed、Web of Science、Cochrane Library、中国知网、万方数据知识服务平台、维普网及中国生物医学文献服务系统中乳腺癌患者经济毒性的相关文献,检索时限为建库至2025年4月,采用Stata 18.0软件进行Meta分析.结果 共纳入21篇文献,总样本量11 762例.Meta分析结果显示乳腺癌患者经济毒性平均得分为23.31.亚组分析显示发展中国家、年龄≤60岁、文化程度高中及以下、农村居住、低收入、自费治疗及接受化疗患者的经济毒性更显著(P<0.05).结论 乳腺癌患者的经济毒性普遍存在,临床应重点关注高危人群,制定针对性干预策略以减轻其经济负担.

Objective To systematically evaluate the occurrence of financial toxicity among breast cancer patients.Methods The relevant literatures on financial toxicity among breast cancer patients in Embase,PubMed,Web of Science,Cochrane Library,CNKI,Wanfang Data Knowledge Service Platform,VIP and SinoMed.The retrieval period was from the establishment of the databases to April 2025.Meta-analysis was conducted using Stata 18.0 software.Results A total of 21 literatures were included,with a total sample size of 11 762 cases.The financial toxicity score of breast cancer patients was 23.31.Subgroup analysis showed significantly higher financial toxicity in patients from developing countries,aged≤60 years,with a high school education or less,residing in rural areas,with low income,with self-funded treatment,or undergoing chemotherapy(P<0.05).Conclusion Financial toxicity is prevalent among breast cancer patients.Clinicians should prioritize high-risk populations and implement targeted interventions to reduce this burden.

杨丽丽;关华;罗姚;杨蕾

成都中医药大学护理学院,四川 成都 610075四川省医学科学院·四川省人民医院健康管理中心,四川 成都 610072成都中医药大学护理学院,四川 成都 610075电子科技大学医学院,四川 成都 610054

医药卫生

乳腺癌经济毒性现状Meta分析

Breast cancerFinancial toxicityCurrent statusMeta-analysis

《中国现代医生》 2026 (19)

43-48,6

10.3969/j.issn.1673-9701.2026.19.010

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