脑卒中吞咽障碍患者吞咽功能恢复的列线图预测模型构建OA
Construction of a nomogram prediction model for the recovery of swallowing function in patients with dysphagia after stroke
目的 探讨影响脑卒中吞咽障碍患者吞咽功能恢复的相关因素并构建列线图预测模型.方法 选取2022年1月至2024年6月南昌大学第二附属医院收治的190例脑卒中吞咽障碍患者,根据患者预后将其分为预后不良组(n=72)和预后良好组(n=118).收集两组患者的临床资料,采用Logistic回归分析影响患者吞咽功能恢复的相关因素.结果 两组患者的年龄、美国国立卫生研究院卒中量表(National Institutes of Health stroke scale,NIHSS)评分、体质量指数(body mass index,BMI)、吸烟史、脑卒中损伤侧、既往脑卒中次数比较差异均有统计学意义(P<0.05);年龄、BMI、NIHSS评分预测患者吞咽功能预后不良的曲线下面积分别为0.657、0.623、0.862;Logistic回归分析结果显示年龄大、有吸烟史、脑卒中损伤左侧、NIHSS评分高均是影响脑卒中吞咽障碍患者吞咽功能恢复的危险因素(P<0.05);构建列线图模型,其内部验证显示C-index为0.774(0.723~0.798),模型预测患者吞咽功能恢复的风险阈值>0.04.结论 高龄、吸烟史、脑卒中损伤左侧、NIHSS评分均是影响脑卒中吞咽障碍患者吞咽功能恢复的危险因素,构建的列线图预测模型临床价值较高.
Objective To explore the related factors influencing the recovery of swallowing function in patients with dysphagia after stroke and construct a nomogram prediction model.Methods A total of 190 patients with dysphagia after stroke admitted to the Second Affiliated Hospital of Nanchang University from January 2022 to June 2024 were selected and divided into poor prognosis group(n=72)and good prognosis group(n=118)according to their prognosis.The clinical data of two groups of patients were collected,and Logistic regression analysis was used to analyze the related factors influencing the recovery of swallowing function in the patients.Results There were statistically significant differences in age,National Institutes of Health stroke scale(NIHSS)score,body mass index(BMI),smoking history,the injured side of stroke,and the number of previous strokes between two groups of patients(P<0.05).The areas under the curve for predicting poor prognosis of patients'swallowing function based on age,BMI and NIHSS score were 0.657,0.623 and 0.862 respectively.The results of Logistic regression analysis showed that advanced age,smoking history,left side injury due to stroke,and high NIHSS score were all risk factors affecting the recovery of swallowing function in patients with dysphagia after stroke(P<0.05).A nomogram model was constructed.Its internal validation showed that the C-index was 0.774(0.723-0.798),and the model predicted that the risk threshold for the recovery of swallowing function in patients was>0.04.Conclusion Advanced age,smoking history,left side injury caused by stroke,and NIHSS score are all risk factors affecting the recovery of swallowing function in patients with dysphagia after stroke.The constructed nomogram prediction model has a relatively high clinical value.
王琼;伍丽华
南昌大学第二附属医院康复医学科,江西 南昌 330006南昌大学第二附属医院康复医学科,江西 南昌 330006
医药卫生
脑卒中吞咽障碍营养支持口部锻炼列线图预测模型
StrokeDysphagiaNutritional supportOral exerciseNomogram predictive modeling
《中国现代医生》 2026 (19)
34-37,68,5
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