基于"筋骨平衡"理论探讨中老年人小腿后群肌对膝骨关节炎的影响OA
Exploring the Influence of the Posterior Group Muscles of the Lower Leg in Middle-Aged and Elderly People on KOA Based on the"Sine-Bone Balance"Theory
目的:分析中老年人腓肠肌和跖肌肌肉的脂肪浸润与膝骨关节炎进展的相关性.方法:回顾性分析2023年1月至2025年2月住院并诊断为原发性单/双侧膝关节病患者80例,采用相关性分析及多因素线性回归分析小腿后群肌肉脂肪浸润与膝关节参数变化、骨关节炎进展程度之间的关联性.结果:膝骨关节炎患者的膝关节内侧间隙与腓肠肌脂肪浸润率(r=-0.027,P<0.001)、跖肌脂肪面积(r=-0.130,P<0.001)、跖肌脂肪浸润率(r=-0.043,P<0.001)呈负相关性;膝关节外侧间隙与腓肠肌脂肪浸润率呈负相关性(r=-0.016,P=0.001).在线性回归分析中,腓肠肌脂肪面积增大、脂肪浸润率升高,对膝关节内外侧间隙有负向影响关系,对股骨远端外侧角有正向影响关系.结论:中老年人小腿腓肠肌脂肪浸润率与膝关节内外侧间隙存在关联性;同时,腓肠肌肌肉质量可能是评估中老年人膝关节退变程度、膝骨关节炎发生发展的重要指标之一,也可能是临床早中期防治膝骨关节炎的关键靶点之一.
Objective:To investigate the correlation between fat infiltration of the gastrocnemius and metatarsal muscles in middle-aged and elderly people and the progression of knee osteoarthritis.Methods:A retrospective analysis was conducted on a total of 80 patients who were hospitalized and diagnosed with primary unilateral or bilateral knee joints between Janu-ary 2023 and February 2025.Correlation analysis and multivariate linear regression analysis were used to analyze the asso-ciation between muscle fat infiltration in the posterior compartment of the lower leg and both knee joint parameter changes and osteoarthritis progression severity.Results:The medial knee joint space of patients with knee osteoarthritis was nega-tively correlated with the fat infiltration rate of the gastrocnemius muscle(r=-0.027,P<0.001),the fat area of the metatarsal muscle(r=-0.130,P<0.001),and the fat infiltration rate of the metatarsal muscle(r=-0.043,P<0.001).The lateral space of the knee joint was negatively correlated with the fat infiltration rate of the gastrocnemius mus-cle(r=-0.016,P=0.001).In the linear regression analy-sis,an increase in the fat area and fat infiltration rate of the gastrocnemius muscle is associated with a reduction in the medial and lateral joint spaces of the knee and an increase in the lateral angle of the distal femur.Conclusion:There is a correlation between the fat infiltration rate of the gastrocnemius muscle in the lower leg of middle-aged and elderly people and the medial and lateral spaces of the knee joint.Meanwhile,the mass of the gastrocnemius muscle may be one of the important indicators for evaluating the degree of knee joint degeneration and the occurrence and development of KOA in middle-aged and elderly people;it may also become one of the key targets for the prevention and treatment of KOA in the early and middle stages of clinical practice.
钱庆;笪巍伟;朱宝财;薛纯纯;李晓锋
上海中医药大学附属市中医医院(上海,200071)||施杞国医大师传承工作室上海中医药大学附属市中医医院(上海,200071)||施杞国医大师传承工作室上海中医药大学附属市中医医院(上海,200071)||施杞国医大师传承工作室上海中医药大学附属市中医医院(上海,200071)||施杞国医大师传承工作室上海中医药大学附属市中医医院(上海,200071)||施杞国医大师传承工作室
医药卫生
膝骨关节炎筋骨平衡腓肠肌跖肌脂肪浸润
knee osteoarthritisbalance of muscles and bonesgastrocnemius musclemetatarsal muscleintramuscular fat
《中国中医骨伤科杂志》 2026 (8)
30-37,8
上海市2022年度"科技创新行动计划"医学创新研究专项项目(22Y11922500)上海市白玉兰人才计划浦江项目(2024PJD915)上海市嘉定区卫生健康委员会中医药项目(2024-KY-ZYY-01)上海市中医医院院级重点专科建设项目(强化专科)-骨伤科
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