前庭性偏头痛无创神经调控治疗的研究进展OA

Vestibular migraine(VM),as a cross-disciplinary disorder of migraine and vestibular dysfunction,has traditionally relied on standard migraine medications,but adverse drug reactions often lead to poor patient compliance.With the continuous advancement of neuromodulation technologies,non-invasive neuromodulation has gradually emerged as a promising therapeutic approach for VM.This review systematically synthesizes and analyzes the latest domestic and international research progress on the application of various non-invasive neuromodulation techniques in the management of vestibular migraine.Specifically,we discuss the mechanisms,clinical evidence,and therapeutic potential of four main modalities:repetitive transcranial magnetic stimulation(rTMS),transcranial direct current stimulation(tDCS),non-invasive vagus nerve stimulation(nVNS),and external trigeminal nerve stimulation(eTNS).Compared with conventional pharmacological interventions,these non-invasive techniques offer distinct advantages,including a favorable safety profile,minimal systemic side effects,and improved patient compliance.Accumulating evidence from clinical studies suggests that these neuromodulation approaches can effectively alleviate both vestibular symptoms(such as vertigo and postural instability)and headache episodes in patients with VM,potentially by modulating cortical excitability,brainstem nuclei activity,and the trigeminal-vestibular pathways connectivity.This review aims to provide a reference for clinicians and researchers interested in the non-invasive management of VM.