猪肌肉生长和脂肪沉积的分子调控机制研究进展OA

In recent years,the improvement in productivity levels and living standards has led people to raise new requirements regarding the taste,flavor,and sensory qualities of pork.This has driven the breeding of high-quality pork to become a focal point in the development of the industry.Muscle growth and fat deposition are key traits that influence pork yield and quality.The core characteristics of muscle growth include myofiber proliferation and hypertrophy,activation of satellite cells,and the cascade reactions of myogenic regulatory factors.Fat deposition involves the dynamic regulation of preadipocyte differentiation,lipid synthesis,and breakdown.Muscle-fat interaction forms an interactive network through secreted factors,metabolic products,and signaling pathways.Muscle-derived factors inhibit fat generation,while hormones secreted by fat tissue reciprocally regulate muscle metabolism.Both achieve a balance of synergy and antagonism through energy allocation.Research on pig muscle growth,fat deposition,and muscle-fat interaction has gradually become a research hotspot in the fields of animal genetics and molecular biology.This article mainly reviews the key regulatory genes and mechanisms of pig muscle growth and fat deposition,with a focus on exploring the cellular and molecular networks and regulatory pathways of muscle-fat interaction,aiming to provide theoretical foundations and strategic references for molecular design breeding and genetic improvement of meat quality traits in pigs.