中频脉冲电刺激联合卡前列素氨丁三醇预防高危剖宫产产妇产后出血的效果及对子宫复旧的影响OA
Effect of Medium-Frequency Pulse Electrical Stimulation Combined with Car-boprost Tromethamine in Preventing Postpartum Hemorrhage and Its Impact on Uterine Involution in High-Risk Cesarean Section Parturients
目的 探讨中频脉冲电刺激联合卡前列素氨丁三醇预防高危剖宫产产妇产后出血的临床效果及对子宫复旧的影响.方法 选取2022年1月至2024年12月在我院行剖宫产分娩且具有产后出血高危因素的100例产妇为研究对象,采用随机数字表法分为对照组与研究组各50例.对照组予以卡前列素氨丁三醇治疗,研究组在对照组基础上给予中频脉冲电刺激.比较两组的产后出血情况、子宫复旧指标、凝血功能指标、产后恢复指标及不良反应.结果 研究组的产后2h、24h出血量均低于对照组,产后出血率低于对照组(P＜0.05).研究组产后第3d、第4d的宫底下降高度均大于对照组,产后42d的子宫三径之和小于对照组,血性恶露持续时间短于对照组(P＜0.05).产后24h,两组的FIB水平均降低,D-D水平均升高,但研究组的变化幅度低于对照组(P＜0.05).研究组的住院时间、泌乳始动时间均短于对照组,产后3d乳汁分泌量高于对照组(P＜0.05).两组的不良反应发生率比较无显著差异(P＞0.05).结论 中频脉冲电刺激联合卡前列素氨丁三醇可协同降低高危剖宫产产妇的产后出血量及产后出血发生率,显著促进子宫复旧,改善凝血功能及泌乳功能,缩短住院时间,且不增加不良反应发生率,是一种安全有效的产后管理方案,值得临床推广应用.
Objective To investigate the clinical effect of medium-frequency pulse electrical stimulation combined with carboprost tromethamine in preventing postpartum hemorrhage and its impact on uterine involution in high-risk cesarean section parturients.Methods A total of 100 parturients with high-risk factors for postpartum hemorrhage who underwent cesarean section in our hospital from January 2022 to December 2024 were enrolled and divided into the control group and the study group by the random number table method,with 50 cases in each group.The control group was treated with carboprost tromethamine alone,while the study group underwent medium-frequency pulse electrical stimulation on the basis of the control group.The postpartum hemorrhage status,uterine involution indicators,coagulation function indicators,postpartum recovery indicators and adverse reactions were compared between the two groups.Results The postpartum blood loss at 2 hours and 24 hours,and the incidence rate of postpartum hemorrhage in the study group were lower than those in the control group(P＜0.05).The fundal height reduction at day 3 and day 4 postpartum in the study group was greater than that in the control group,the sum of the three uterine dimensions at 42 days postpartum was smaller than that in the control group,and the duration of bloody lochia was shorter than that in the control group(P＜0.05).At 24 hours postpartum,the FIB levels decreased in both groups,and the D-D levels increased in both groups,but the magnitudes of change in the study group were lower than those in the control group(P＜0.05).The hospitalization duration and time to onset of lactation in the study group were shorter than those in the control group,and the breast milk production volume at 3 days postpartum was higher than that in the control group(P＜0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups(P＞0.05).Conclusions Medium-frequency pulse electrical stimulation combined with carboprost tromethamine can synergistically reduce the amount of postpartum blood loss and the incidence of postpartum hemorrhage in high-risk cesarean section parturients,significantly promote uterine involution,improve coagulation function and lactation function,and shorten hospitalization duration without increasing the incidence of adverse reactions.It is a safe and effective postpartum management strategy and is worthy of clinical promotion.
袁远;李晓燕;关梦珂;李娜娜;靳利平
郑州市中心医院产科,河南郑州 450000郑州市中心医院产科,河南郑州 450000郑州市中心医院产科,河南郑州 450000郑州市中心医院产科,河南郑州 450000郑州市中心医院产科,河南郑州 450000
医药卫生
中频脉冲电刺激卡前列素氨丁三醇高危剖宫产产后出血子宫复旧
Medium-frequency pulse electrical stimulationCarboprost tromethamineHigh-risk cesarean sectionPostpartum hem-orrhageUterine involution
《临床医学工程》 2026 (7)
774-778,5
河南省医学科技攻关计划联合共建项目(LHGJ20220863)
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