Chirality-Dependent Supramolecular Biomaterials Remodeling of Scar Microenvironment via Integrin-Mediated Regulation for Hypertrophic Scars TherapyOA
Chirality-Dependent Supramolecular Biomaterials Remodeling of Scar Microenvironment via Integrin-Mediated Regulation for Hypertrophic Scars Therapy
Xueqian Wang;Chengyao Han;Hongrui Shan;Jinjin Li;Beibei Wu;Yixin Zhang;Ke Li;Chuanliang Feng
State Key Lab of Metal Matrix Composites,Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs,School of Materials Science and Engineering,Shanghai Jiao Tong University,Shanghai 200240,People's Republic of China||Department of Plastic and Reconstructive Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,People's Republic of ChinaDepartment of Plastic and Reconstructive Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,People's Republic of ChinaResearch Center of Precision Sensing and Control,Institute of Automation,Chinese Academy of Sciences,Beijing 100190,People's Republic of ChinaNational Key Laboratory of Advanced Micro and Nano Manufacture Technology,Shanghai Jiao Tong University,Shanghai 200240,People's Republic of ChinaState Key Lab of Metal Matrix Composites,Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs,School of Materials Science and Engineering,Shanghai Jiao Tong University,Shanghai 200240,People's Republic of ChinaDepartment of Plastic and Reconstructive Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,People's Republic of ChinaDepartment of Plastic and Reconstructive Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,People's Republic of ChinaState Key Lab of Metal Matrix Composites,Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs,School of Materials Science and Engineering,Shanghai Jiao Tong University,Shanghai 200240,People's Republic of China
ChiralityBiomaterialHypertrowpzhic scarsIntegrinFibroblasts
ChiralityBiomaterialHypertrowpzhic scarsIntegrinFibroblasts
《纳微快报（英文）》 2026 (10)
285-306,22
This work was supported by National Key Research and Development Program of China(2024YFB3814600)and the Leading Talents in Science and Technology Innovation under the National Ten Thousand Talents Plan,the National Natural Science Foundation of China(52533014,82172222,82000456,82402906),the Science and Technology Commission of Shanghai Municipality(No.25CL2900600),Shanghai Pujiang Program(20PJ1407400),China Postdoctoral Science Foundation General Fund(2025M780112),and Shanghai Jiao Tong University"Star Project"of Biomedical Multi-discipline Research Program(YG2024ZD13).All animal experimental procedures were per-formed according to the Ethical Committee for Animal Experi-ments of Shanghai Jiao Tong University(China,A2022048).
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