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大语言模型赋能乳腺外科精准决策与全周期病人管理OA

Large language models empower precision decision-making in breast surgery and whole-cycle patient management

中文摘要英文摘要

早期乳腺癌诊疗具有病程长、异质性强、数据多源异构及决策动态演变等特点,传统多学科诊疗(MDT)决策模式面临效率低、全周期管理断层等挑战.大语言模型(LLM)凭借处理非结构化文本、整合多源数据及辅助临床推理的优势,为解决上述问题提供了新路径.本文阐述LLM在乳腺癌MDT决策中的应用价值,重点分析个体化治疗推荐智能体、多智能体协同及临床决策证据生成与融合三种核心方法,并从临床知识库动态更新、病例数据库与模型深度融合、人机协作病例管理及类OpenClaw智能医生助理四个方面,提出未来发展建议,为推动乳腺癌全周期精准诊疗及MDT模式优化提供参考.

Early-stage breast cancer diagnosis and treatment are characterized by long disease course,high heterogeneity,multi-source and heterogeneous data,and dynamic evolving decision-making.The traditional multidisciplinary team(MDT)decision-making model faces challenges such as low efficiency and fragmented whole-cycle management.Large language models(LLMs)provide a new approach to solving these problems by virtue of their advantages in processing unstructured text,integrating multi-source data,and assisting clinical reasoning.This paper elaborated on the application value of LLMs in breast cancer MDT decision-making,focused on analyzing three core methods:personalized treatment recommendation agents,multi-agent collaboration,and clinical decision-making evidence generation and fusion.Furthermore,it proposed future development strategies across four dimensions:dynamic update of clinical knowledge bases,in-depth integration of case databases and models,human-machine collaborative case management,and OpenClaw-style intelligent physician assistant,providing references for promoting whole-cycle precise diagnosis and treatment of breast cancer and optimizing the MDT model.

朱能军;曹健;陈小松;朱思吉

上海大学计算机工程与科学学院,上海 200444上海交通大学计算机学院,上海 200240上海交通大学医学院附属瑞金医院普外科 乳腺疾病诊治中心,上海 200025上海交通大学医学院附属瑞金医院普外科 乳腺疾病诊治中心,上海 200025

医药卫生

大语言模型乳腺癌多学科诊疗决策精准诊疗全周期管理

Large language model(LLM)Breast cancerMultidisciplinary team(MDT)decision-makingPrecise diagnosis and treatmentWhole-cycle management

《外科理论与实践》 2026 (3)

185-190,6

上海体育科技项目(26Q013)上海市卫健委医学新技术研究与转化种子计划重点项目(2025ZZ1009)上海市卫健委智慧医疗专项(2025ZHYL003)国家自然科学基金(82573726)

10.16139/j.1007-9610.2026.03.02

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