2003-2023年北京市房山区居民肺癌死亡特征及减寿分析OA
Analysis of mortality and years of life lost of lung cancer among residents in Fangshan district,Beijing,from 2003 to 2023
目的 分析2003-2023年北京市房山区居民肺癌死亡特征和寿命损失,为优化区域肺癌防控提供依据.方法 基于2003-2023年北京市人口死亡登记报告信息系统的数据,计算分析房山区肺癌粗死亡率(crude mortality rate,CMR)、标化死亡率(standardized mortality rate,SMR)、潜在减寿年数(potential years of life lost,PYLL)和平均减寿年数(average years of life lost,AYLL)等指标,运用 Joinpoint回归模型计算年度变化百分比(annual percent change,APC)和平均APC(average APC,AAPC),以评估死亡率的时间变化趋势.结果 2003-2023年,房山区居民肺癌CMR 47.58/10万,SMR为34.93/10万.CMR整体呈上升趋势(AAPC=4.305%,P<0.01),人口因素贡献率达54.38%.男性CMR(63.48/10万)是女性(31.60/10万)的2.01倍.全人群SMR在研究期间总体呈波动变化,长期变化趋势差异无统计学意义(AAPC=1.121%,P=0.118).全人群PYLLR上升,AYLL从2003年的12.69年/人降至2023年的9.28年/人.男性疾病负担更重,2023年PYLLR(5.25‰)是女性(2.00‰)的2.62倍.房山区居民肺癌CMR在40岁后随年龄增长呈上升趋势,60岁后上升显著,80~84岁达峰值.结论 人口因素是房山区肺癌CMR上升的主因,而SMR与AYLL下降体现筛查技术、诊疗水平和居民健康意识提升.男性疾病负担高于女性.建议完善早筛体系和优化高危人群管理以持续降低负担.
Objective To analyze the mortality and years of life lost of lung cancer in Fangshan district,Beijing,from 2003 to 2023 to in-form regional prevention and control strategies.Methods Using the data from Beijing population death registration and reporting informa-tion system from 2003 to 2023,indicators including crude mortality rate(CMR),standardized mortality rate(SMR),potential years of life lost(PYLL),and average years of life lost(AYLL)of lung cancer in Fangshan district were calculated.Joinpoint regression was used to estimate annual percent change(APC)and average APC(AAPC)for temporal trend analysis.Results From 2003 to 2023,the CMR of lung cancer was 47.58/100 000 and the SMR was 34.93/100 000.The CMR presented an overall upward trend(AAPC=4.305%,P<0.01).with demo-graphic factors responsible for 54.38%of the rise.Male CMR(63.48/100 000)was 2.01 times that of females(31.60/100 000).In the overall population,the SMR exhibited fluctuations during the study period,its long-term trend was not statistically significant(AAPC=1.121%,P=0.118);PYLL rate(PYLLR)increased;AYLL declined from 12.69 to 9.28 years per person from 2003 to 2023.The burden remained heavier in males:in 2023,male PYLLR(5.25‰)was 2.62 times that of females(2.00‰).The CMR of lung cancer in Fangshan district in-creased with age after age 40,rising markedly after age 60,and peaking in the 80-84 age group.Conclusions Demographic factors is the main driver of rising CMR of lung cancer in Fangshan district,whereas falling SMR and AYLL likely reflect improved screening,diagnosis,treatment,and health awareness.The disease burden is substantially greater in males.Strengthening early screening and optimizing the man-agement of high-risk groups are recommended to further reduce lung cancer mortality and burden.
龚海英;张丽娜;康喜春;赵耀
北京市房山区疾病预防控制中心(卫生健康监督所),北京 102488北京市房山区疾病预防控制中心(卫生健康监督所),北京 102488北京市房山区疾病预防控制中心(卫生健康监督所),北京 102488北京市房山区疾病预防控制中心(卫生健康监督所),北京 102488
肺癌死亡潜在减寿年数
lung cancermortalitypotential years of life lost
《实用肿瘤杂志》 2026 (4)
325-331,7
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