雷公藤甲素防治农田害鼠田间药效及安全性评价OA

To determine the control effect of 0.25 mg/kg triptolide granules against farmland rodents and evaluate its field persistence,palatability and safety,and to provide technical support and alternative products for future farmland rodent control,the field efficacy trials were carried out in Sandu County,Guizhou Province to comprehensively evaluate the control effect of 0.25 mg/kg triptolide granules against farmland rodents and the safety to non-target organisms.The results showed that 0.25 mg/kg triptolide granules had a certain control effect on farmland rodents.The control effects based on trapping rate at 30 d,60 d and 90 d after application were 60.10％,71.03％and 63.04％,respectively.The best control effect was observed at 60 d after application,and a clear control effect remained at 90 d after application,indicating relatively long field persistence.At the same time,the granules also showed a certain inhibitory effect on rodent pregnancy rate,with control effect ranging from 50.00％to 100.00％during 30～90 days of application.The product showed good palatability,with average removal rate and feeding rate over 5 days of 24.27％and 49.09％,respectively.It was also safe to non-target organisms.Overall,0.25 mg/kg triptolide granules are an ideal option for the green control of farmland rodents and can be widely promoted as a rodenticide for rotational use in farmland.For emergency control,they may be used in combination with highly effective,low-toxicity and low-residue anticoagulant rodenticides.