防风及其药对研究OA
Research on Fangfeng(Saposhnikoviae Radix)and Its Herb Pairs
防风是中医"风药"的代表之一,被誉为"治风通用药",最早可追溯至《神农本草经》,具有祛风解表、胜湿止痛之功.现代研究表明,防风具有解热、镇痛、抗炎、抗过敏、调节免疫等多种药理作用.在临床应用中,防风-黄芪、防风-荆芥、防风-白术、防风-羌活、防风-乌梅、防风-白芍、防风-甘草等经典药对组合在治疗感冒、风湿痹痛、皮肤瘙痒、脱肛泄泻以及调理表虚不固等多种病证中展现出显著的协同增效效果.该文旨在系统梳理近年来防风单味药及其临床常用药对在药理作用机制与临床应用方面的研究进展,综述其研究现状,以期为防风及其核心配伍药对的深入开发、现代化应用及新药研发提供科学依据和创新思路.
Fangfeng(Saposhnikoviae Radix)is a quintessential"wind-dispelling"herb in traditional Chinese medicine(TCM),renowned as a"universal remedy for wind disorders."Its earliest documented use can be traced to the Divine Farmer's Materia Medica.In TCM theory,it is credited with the functions of dispelling wind,releasing the exterior,overcoming dampness,and relieving pain.Modern pharmacological research has revealed that Fangfeng(Saposhnikoviae Radix)possesses a wide range of biological activities,including antipyretic,analgesic,anti-inflammatory,anti-allergic,and immunomodulatory effects.In clinical practice,several classic herb pairs involving Fangfeng(Saposhnikoviae Radix)-Huangqi(Astragali Radix),Fangfeng(Saposhnikoviae Radix)-Jingjie(Schizonepetae Herba),Fangfeng(Saposhnikoviae Radix)-Baizhu(Atractylodis Macrocephalae Rhizoma),Fangfeng(Saposhnikoviae Radix)-Qianghuo(Notopterygii Rhizoma Et Radix),Fangfeng(Saposhnikoviae Radix)-Wumei(Mume Fructus),Fangfeng(Saposhnikoviae Radix)-Baishao(Paeoniae Radix Alba),Fangfeng(Saposhnikoviae Radix)-Gancao(Glycyrrhizae Radix Et Rhizoma),demonstrate significant synergistic and efficacy-enhancing effects.These combinations are widely used to treat various conditions,including common cold,rheumatic arthralgia,skin pruritus,rectal prolapse with diarrhea,as well as to regulate exterior deficiency and insecurity.This article aims to systematically review recent research progress on both the single herb Fangfeng(Saposhnikoviae Radix)and its commonly used clinical herb pairs,focusing on their pharmacological mechanisms and clinical applications.By summarizing the current state of research,it seeks to provide a scientific basis and innovative insights for the further development,modern application,and new drug research of Fangfeng(Saposhnikoviae Radix)and its core herbal combinations.
张嘉慧;岳新;牧亚峰
河南中医药大学第一附属医院,河南 郑州 450000||河南中医药大学,河南 郑州 450000河南中医药大学第一附属医院,河南 郑州 450000||河南中医药大学,河南 郑州 450000河南中医药大学第一附属医院,河南 郑州 450000||河南中医药大学,河南 郑州 450000
医药卫生
防风药理作用药对研究
Fangfeng(Saposhnikoviae Radix)pharmacological effectsherb pairsresearch
《辽宁中医药大学学报》 2026 (8)
50-54,5
河南省中医药科学研究专项课题(2022JDZX107)河南省卫生健康委员会国家中医药传承创新中心联合共建科研专项课题(2024ZXZX1070)
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