环肽的功能及研究进展OA

As a type of polypeptide with a cyclic structure,cyclic peptides have shown significant advantages in the field of drug research and development due to their unique physicochemical properties between small molecules and proteins.Their cyclic structures are formed by amide bonds or other chemically stable bonds,which endows cyclic peptides with higher metabolic stability,target affinity and membrane permeability,and overcome the limitations of linear peptides such as easy degradation and insufficient targeting of small molecules.This paper focused on the application of cyclic peptides in the field of animal husbandry and veterinary medicine,reviewed their main acquisition methods and synthesis methods,and summarized their pharmacological effects and specific application cases in antibacterial and antiviral aspects.This paper further discussed the application potential of cyclic peptides in antiparasitic infection and intestinal microbiota regulation,and discussed the prospects future technology optimization and industrialization path in livestock production,aiming to provide reference for the clinical veterinary application of cyclic peptides.