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医用植入可降解镁合金力学性能强化策略研究进展OA

Research progress on strategies for enhancing the mechanical properties of biodegradable magnesium alloys for medical implants

中文摘要英文摘要

镁合金的弹性模量与人骨接近,能有效减轻"应力遮挡效应",并避免患者二次取出手术,且因其优异的生物相容性和可降解特性,常被应用于骨科和心血管领域.然而,其相对较低的强度、较差的塑性及在体内过早的力学性能失效,制约了其在承重骨植入物中的广泛应用.本文总结了镁合金通过合金化、热处理及塑性变形等工艺改进机械性能的研究,重点讨论了不同合金元素如钙、锌、锶等通过细晶强化、固溶强化等方式对强度与塑性的影响机制;阐述了固溶处理(T4)、时效处理(T5、T6)对微观组织和第二相的调控作用;探讨了热挤压、热轧等塑性变形工艺在细化晶粒、优化织构方面的贡献.最后展望了通过复合塑性变形与热处理、开发新型合金体系以及利用增材制造技术来协调材料强度、韧性及降解过程中机械完整性等未来研究方向,以期为高性能医用镁合金的研发提供理论参考.

The elastic modulus of magnesium alloys is similar to that of human bone,which can effectively avoid the"stress shielding effect"and eliminate the need for secondary removal surgeries.Due to their excellent biocompatibility and degradability,magnesium alloys are commonly used in orthopedics and cardiovascular fields.However,their relatively low strength,limited ductility,and premature mechanical performance failure in vivo limit their widespread application in load-bearing bone implants.This review summarizes the research progress on improving the mechanical properties of magnesium alloys through alloying,heat treatment processes,and plastic deformation.It focuses on the influence mechanisms of different alloying elements,such as calcium,zinc,and strontium,on strength and plasticity through grain refinement,solid solution strengthening,and other mechanisms.The role of solution treatment(T4),aging treatment(T5,T6)in regulating microstructure and secondary phases is discussed.Additionally,the contributions of plastic deformation processes,such as hot extrusion and hot rolling,in refining grain size and optimizing texture are explored.Finally,future research directions are envisioned,including the combination of composite plastic deformation and heat treatment,the development of new alloy systems,and the use of additive manufacturing technologies to balance material strength,toughness,and mechanical integrity during degradation,aiming to provide theoretical references for the development of high-performance magnesium alloys for medical applications.

郑智展;沈琳;王慧杰;姬文豪;周丽丽

赣南医科大学医学信息工程学院,江西 赣州 341000赣南医科大学医学信息工程学院,江西 赣州 341000赣南医科大学医学信息工程学院,江西 赣州 341000赣南医科大学医学信息工程学院,江西 赣州 341000赣南医科大学医学信息工程学院,江西 赣州 341000

矿业与冶金

医用镁合金骨植入物力学性能优化微观组织调控生物可降解

Medical magnesium alloysBone implantsMechanical propertyMicrostructural regulationBiodegradable

《赣南医科大学学报》 2026 (7)

649-656,8

国家自然科学基金项目(52261023)

10.3969/j.issn.2097-7174.2026.07.009

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