生成式人工智能辅助心血管疾病诊疗决策的信任构建与挑战OA
Trust Building and Challenges of Generative Artificial Intelligence-Assisted Cardiovascular Diagnosis and Treatment Decision-Making
生成式人工智能在心血管疾病诊疗中展现出病历生成、个体化建议和医患沟通等应用潜力,但其"黑箱"特性、幻觉问题与医学伦理挑战引发了医生与管理者的信任危机.本文从技术与非技术双路径出发,系统探讨了心血管领域对人工智能准确性、可解释性与鲁棒性的特殊要求.在技术层面,分析了注意力可视化、思维链提示与检索增强生成(RAG)等可解释性方法,以及不确定性量化在风险预警中的作用.在非技术层面,强调严格的临床验证、跨法域法规框架与责任归属界定,以及人机协作模式与医生人工智能素养培养对构建信任的关键意义.文章进一步总结了当前面临的技术瓶颈、数据困境与接受障碍,并提出技术融合、协同决策与动态可信框架的未来方向.信任是多维度的系统工程,需技术、制度与人文协同推进,方能实现生成式人工智能在心血管临床中的可信落地.
In cardiovascular diagnosis and treatment,generative artificial intelligence(Generative AI)demonstrates significant potential in efficiently generating medical records,providing personalized diagnostic and therapeutic recommendations,and optimizing physician-patient communication.However,its inherent"black-box"nature,unpredictable hallucination phenomena,and complex medical ethics have precipitated a crisis of trust among clinicians and healthcare administrators.This paper systematically explores the specific requirements for AI accuracy,interpretability,and robustness in the cardiovascular field from both technical and non-technical perspectives.On the technical front,the paper analyzes interpretability methods such as attention visualization,thought-chain prompts,and Retrieval-Augmented Generation(RAG),as well as the role of uncertainty quantification in risk warning.On the non-technical front,it emphasizes the critical importance of rigorous clinical validation,cross-jurisdictional regulatory frameworks,and the delineation of liability,as well as human-AI collaboration models and the cultivation of AI literacy among physicians for build-ing trust.The article further summarizes the current technical bottlenecks,data challenges,and barriers to acceptance,and proposes future directions involving technological convergence,collaborative decision-making,and dynamic trust frameworks.Trust is a multidi-mensional systems engineering endeavor that requires the coordinated advancement of technology,institutional frameworks,and humanistic considerations to achieve the reliable implementation of generative AI in cardiovascular clinical practice.
张春祥;苏渝杰
西南医科大学附属医院 心血管内科(泸州 646000)||西南医科大学 心血管医学研究所,医学电生理学教育部重点实验室,医学电生理四川省重点实验室(泸州 646000)||西南医科大学 教育部心血管代谢疾病基础医学研究创新中心(泸州 646000)||西南医科大学 泸州市核酸医学重点实验室(泸州 646000)西南医科大学附属医院 心血管内科(泸州 646000)||西南医科大学 心血管医学研究所,医学电生理学教育部重点实验室,医学电生理四川省重点实验室(泸州 646000)||西南医科大学 教育部心血管代谢疾病基础医学研究创新中心(泸州 646000)||西南医科大学 泸州市核酸医学重点实验室(泸州 646000)
医药卫生
生成式人工智能心血管疾病临床决策支持信任构建可解释性人机协作
Generative artificial intelligenceCardiovascular diseaseClinical decision supportTrust buildingInterpretabil-ityHuman-machine collaboration
《西南医科大学学报》 2026 (4)
409-414,6
国家自然科学基金(U23A20398)国家科技重大专项项目(2024ZD0537707)四川省科技计划项目(2025YFRG0005)泸州市人民政府-西南医科大学科技战略合作项目(2025LZXNYDPD01)西南医科大学研究创业基金(00040155)
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