Factors affecting color vision:a systematic reviewOA
●AIM:To summarize the influencing factors of color vision and their clinical implications,with an emphasis on the roles of genetic,environmental,demographic factors as well as ocular and systemic disorders.●METHODS:Relevant literatures published from 2014 to 2024 were systematically retrieved from six databases including PubMed,Embase,Scopus,Web of Science,Cochrane Library,and Google Scholar.Search terms mainly covered color blindness,color vision deficiency(CVD),prevalence,incidence,protan,deutan,tritan,determinants,and risk factors.Eligible original English studies were screened according to predefined inclusion and exclusion criteria.Data extraction and quality evaluation were independently completed by two researchers.Qualitative systematic review was finally performed due to obvious inter-study heterogeneity.●RESULTS:A total of 50 eligible studies were enrolled.The prevalence of CVD was markedly higher in males than in females.Age,gender,ethnicity,and occupation were closely correlated with CVD.Males and individuals aged over 60y were more vulnerable to red-green CVD.Occupational ultraviolet radiation exposure,systemic diseases including diabetes mellitus and hypertension,as well as optic nerve lesions were confirmed as vital risk factors for abnormal color vision.●CONCLUSION:Apart from genetic and congenital factors,environmental exposure,aging,occupational characteristics,and various ocular and systemic diseases that impair retinal and optic nerve function can also affect color vision function.Clarifying these influencing factors helps ophthalmologists formulate targeted prevention schemes and individualized clinical interventions.Further well-designed longitudinal studies covering more diverse populations are still required in this field.
Faezeh Fayaz;Ebrahim Jafarzadehpur;Morad Amir Ahmad;Rasoul Amini Vishteh;Mohammad Reza Pishnamaz;Mohammad Saeid Hoseinzade;Leila Mirzaee Saba;MohammadKamali;Abbasali Yekta;Mehdi Khabazkhoob
Rehabilitation Research Center,Department of Optometry,School of Rehabilitation Sciences,Iran University of Medical Sciences,Tehran 1545913487,IranNoor Ophthalmology Research Center,Noor Eye Hospital,Tehran 1983963113,IranDepartment of Optometry&Physiotherapy,Erbil Technical&Medical Health Collage,Erbil Polytechnic University,Erbil,Kurdistan Region 44001,IraqRehabilitation Research Center,Department of Optometry,School of Rehabilitation Sciences,Iran University of Medical Sciences,Tehran 1545913487,IranRehabilitation Research Center,Department of Optometry,School of Rehabilitation Sciences,Iran University of Medical Sciences,Tehran 1545913487,IranRehabilitation Research Center,Department of Optometry,School of Rehabilitation Sciences,Iran University of Medical Sciences,Tehran 1545913487,IranNoor Research Center for Ophthalmic Epidemiology,Noor Eye Hospital,Tehran 1968653111,IranDepartment of Rehabilitation Management,Rehabilitation Research Center,School of Rehabilitation Sciences,Iran University of Medical Sciences,Tehran 1545913487,IranDepartment of Optometry,School of Paramedical Sciences,Mashhad University of Medical Sciences,Mashhad 1394491388,IranDepartment of Medical Surgical Nursing,School of Nursing and Midwifery,Shahid Beheshti University of Medical Sciences,Tehran 1983969411,Iran
医药卫生
color visioninfluencing factorsgeneticsenvironmentagingocular and systemic diseases
《International Journal of Ophthalmology(English edition)》 2026 (7)
P.1395-1405,11
Supported by Deputy of Research of Iran University of Medical Sciences,Tehran,Iran.
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