首页|期刊导航|Acta Biochimica et Biophysica Sinica|Single-cell dissection of avian(chicken)H1N1 influenza virus coinfection dynamics in mammalian(mouse)and avian(chicken)hosts

Single-cell dissection of avian(chicken)H1N1 influenza virus coinfection dynamics in mammalian(mouse)and avian(chicken)hostsOA

中文摘要

The cross-species transmission mechanisms and host-specific immune adaptations of avian H1N1 influenza viruses remain poorly understood.Avian H1N1 influenza viruses represent a persistent zoonotic threat owing to their evolutionary plasticity and capacity for cross-species transmission.These viruses,while endemic in avian reservoirs,frequently acquire mutations that enable spillover into mammalian hosts,including humans,pigs,and other intermediate species[1].

Yuelong Zhou;Xueyu Zhang;Fei Chen;Weidong Deng;Pu Wang

Yunnan Provincial Key Laboratory of Animal Nutrition and Feed,Faculty of Animal Science and Technology,Yunnan Agricultural University,Kunming 650201,China Hangzhou Xiaoshan Donghai Aquaculture Co.,Ltd.,Hangzhou 311200,ChinaHangzhou Xiaoshan Donghai Aquaculture Co.,Ltd.,Hangzhou 311200,ChinaHangzhou Xiaoshan Donghai Aquaculture Co.,Ltd.,Hangzhou 311200,ChinaYunnan Provincial Key Laboratory of Animal Nutrition and Feed,Faculty of Animal Science and Technology,Yunnan Agricultural University,Kunming 650201,ChinaYunnan Provincial Key Laboratory of Animal Nutrition and Feed,Faculty of Animal Science and Technology,Yunnan Agricultural University,Kunming 650201,China College of Animal Science and Technology&College of Veterinary Medicine,Zhejiang A&F University,Key Laboratory of Applied Technology on Green Eco-Healthy Animal Husbandry of Zhejiang Province,Provincial Engineering Research Center for Animal Health Diagnostics&Advanced Technology,Zhejiang International Science and Technology Cooperation Base for Veterinary Medicine and Health Management,China Australia Joint Laboratory for Animal Health Big Data Analytics,Hangzhou 311300,China

农业科技

evolutionary plasticityavian influenzaacquire mutationszoonotic threatH Ncoinfectionmouseavian h n influenza viruses

《Acta Biochimica et Biophysica Sinica》 2026 (4)

P.920-924,5

supported by the grant from Beijing Genomics Institute(No.32360231 to Y.Z.).

10.3724/abbs.2025184

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