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肝癌共病心血管疾病的辨治OA

Differentiation and Treatment of Hepatic Cancer Comorbid with Cardiovascular Disease

中文摘要英文摘要

随着肿瘤生存期及抗肿瘤治疗周期的延长,肝癌共病心血管疾病已成为临床亟待攻克的难题.肝癌与心血管疾病的共病在临床上呈现出"旧疾共存"与"新伤叠加"的双重特征.本文基于中医"心肝相关"理论,系统阐释了心、肝二脏在藏象、五行、经络及气血神志方面的生理维系,揭示了肝癌共病心血管疾病以"本虚标实,毒瘀互结,木火失调"为核心的病机及其动态演变规律.针对这一病理过程,本文确立了"心肝同治"的整体治疗原则,构建了"辨主次以定标本缓急,抓主证以立核心治法,合三因以灵活加减"的临床辨治体系.该体系通过调和气血阴阳、攻补兼施,实现对肿瘤进展与多源性心血管风险的双重管控,为肝癌患者的高质量"带瘤生存"保驾护航.

With the prolongation of tumor survival and the long-term duration of anti-tumor therapies,hepatic cancer comorbid with cardiovascular disease(CVD)has emerged as a complex clinical challenge urgently requiring resolution.The comorbidity of hepatic cancer and CVD presents dual clinical features characterized by the"coexistence of pre-existing diseases"and the"superposition of new injuries".Based on traditional Chinese medicine(TCM)theory of"heart-liver correlation",this paper systematically elucidates the physiological maintenance of heart and liver in terms of visceral manifestations,five phases,meridians,and qi,blood,and spirit.It reveals that the core pathogenesis of hepatic cancer comorbid with CVD is characterized by"deficiency in the root and excess in the branch,intertwining of toxin and stasis,and imbalance between wood and fire",along with its dynamic evolutionary rules.Aiming at this pathological process,this paper establishes the holistic therapeutic principle of"simultaneous treatment of heart and liver",and constructs a clinical syndrome differentiation and treatment system involving"distinguishing primary and secondary to determine priorities,focusing on chief symptoms to establish core therapeutic methods,and adapting to seasonal,regional,and individual factors for flexible modifications".This system aims to achieve dual management of tumor progression and multi-source cardiovascular risks by harmonizing qi,blood,yin,and yang while applying both attacking and tonifying methods,thereby supporting high-quality"survival with tumor"in patients with hepatic cancer.

刘紫凤;李晏龙;余玲;陈昫;陈壮忠;庞润华;曾江涛

广州中医药大学茂名医院/茂名市中医院脾胃肝病科,广东 茂名 525000中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京 100000广州中医药大学第一附属医院肿瘤中心,广东 广州 510000广州中医药大学第一附属医院肝胆病科,广东 广州 510000广州中医药大学第一附属医院肿瘤中心,广东 广州 510000广州中医药大学第一附属医院肝胆外科,广东 广州 510000广州中医药大学茂名医院/茂名市中医院脾胃肝病科,广东 茂名 525000

医药卫生

肝癌心血管疾病心肝相关心肝同治共病辨证论治

hepatic cancercardiovascular diseaseheart-liver correlationsimultaneous treatment of heart and livercomorbiditysyndrome differentiation and treatment

《中医肿瘤学杂志》 2026 (3)

20-28,9

第五批全国中医临床优秀人才研修项目(编号:国中医药人教函[2022]1号)广东省医学科学技术研究基金项目(编号:A2024636)广州市科技计划项目(编号:2023A03J0289)2025年中国科协青年科技人才培育工程博士生专项计划.

10.19811/j.cnki.ISSN2096-6628.2026.05.004

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