加减通痹方联合中药熏蒸治疗寒湿痹阻型类风湿关节炎临床疗效OA

Objective:To analyze the effect of Modified Tongbi Formula combined with traditional Chinese medicine fumigation on rheumatoid arthritis(RA)syndrome of cold-dampness obstruction.Methods:168 patients with RA cold-dampness obstruction syndrome admitted to the Eastern Theater General Hospital from April 2021 to June 2024 were divided into 2 groups according to different treatment methods.83 patients in the control group were treated with traditional Chinese medicine fumigation,and 85 patients in the observation group were treated with Modified Tongbi Formula.The therapeutic effect of the two groups was compared.Results:The treatment effect of observation group was compared with control group(P<0.05).After treatment,TCM syndrome score,28 joint activity score(DAS28)and clinical disease activity index(CDAI)in observation group were lower than those in control group(P<0.05).After treatment,the levels of rheumatoid factor(RF),C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),D-dimer(D-D)and immunoglobulin(IgG,IgA,IgM)in observation group were lower than those in control group(P<0.05).The incidence of adverse reactions was compared between observation group and control group(P>0.05).Conclusion:Modified Tongbi Formula combined with traditional Chinese medicine fumigation has a remarkable effect,which can significantly reduce the score of traditional Chinese medicine symptoms,significantly reduce the level of inflammation,enhance immune function,reduce disease activity,and do not increase adverse drug reactions.