中医药治疗的系统性红斑狼疮合并血液损害研究进展OA

Hematological damage is systemic lupus erythematosus is a common comorbidity,and traditional Chinese medicine(TCM)believes that the core pathogenesis of this disease is deficiency and excess,and deficiency,toxicity,heat,and stasis run through the dynamic evolution process.At present,the treatment is mainly based on staged and typed treatment,and the treatment method of attacking poison and dispelling pathogen in the acute stage,nourishing vital qi in the chronic stage,and dissolving blood stasis is always proposed.In terms of mechanism of action,it has been verified that it can playa role by regulating immune homeostasis,inhibiting inflammatory cascades,improving microcirculation,and improving metabolism and microecology.At the same time,there are many studies on the correlation between TCM syndrome and laboratory indicators,which provides a basis for the objectification of TCM syndrome patterns.This paper expounds the research progress of TCM in systemic lupus erythematosus with hematological damage from the perspectives of TCM theory and modern mechanism,aiming to provide a theoretical basis for clinical optimization of treatment plans.