赛霉安散对血热肠燥型肛裂术后创面愈合影响的临床观察OA

Objective:To investigate the effect of Sai Mei An San(赛霉安散)wound healing after surgery for anal fissure with the pattern of intestinal dryness due to blood-heat.Methods:Using a simple randomization method,a random number table was generated by SPSS 26.0 software.The of total 226 eligible inpatients from Quanzhou Hospital of Traditional Chinese Medicine were randomly divided into a treatment group(Sai Mei An San plus Vaseline Gauze Dressing Change)and a control group(Vaseline Gauze Dressing Change alone),each group containing 113 cases.The observation period lasted until the wound was completely healed.During this period,corresponding observation indicators including wound granulation tissue growth status,wound pain level,and wound healing time were observed,recorded,and efficacy was evaluated on postoperative day 1,day 7,day 14,and at the time of complete healing.The data underwent relevant statistical analysis.Finally,the effect of Sai Mei An San on wound healing after surgery for anal fissure with the pattern of intestinal dryness due to blood-heat was summarized,aiming to provide a more effective treatment plan for postoperative anal fissure wound recovery and provide a theoretical basis for the clinical application and promotion of Sai Mei An San.Results:Comparison of granulation tissue growth scores between the treatment group and the control group showed statistically significant differences on postoperative day 7(P=0.037)and on postoperative day 14(P=0.020)compared with before treatment.Furthermore,the granulation scores in the treatment group were overall lower than those in the control group at the same time points(day 7 and 14).Comparison of wound pain level scores showed no statistically significant difference on postoperative day 7(P=0.067),but a statistically significant difference on postoperative day 14(P=0.026),with the pain score in the treatment group significantly lower than that in the control group on day 14.Comparison of wound healing time showed a statistically significant difference(P<0.001),with the healing time in the treatment group significantly shorter than that in the control group.Comparison of the comprehensive efficacy evaluation between the two groups showed a statistically significant difference(P=0.042),with the number of markedly effective cases in the treatment group significantly higher than that in the control group.Conclusion:Sai Mei An San has the effects of astringing dampness and stopping bleeding,clearing heat and detoxifying,relieving pain,and promoting tissue regeneration.In the repair of postoperative wounds for anal fissure with the pattern of intestinal dryness due to blood-heat,it helps promote good granulation tissue growth,alleviate pain,and shorten healing time.Its efficacy is significant and it is worthy of clinical promotion and application.