主动风险干预联合早期俯卧位通气护理在新生儿呼吸窘迫综合征中的应用研究OA
Application of active risk intervention combined with early prone ventilation nursing in neonatal respiratory distress syndrome
目的 探讨主动风险干预联合早期俯卧位通气在新生儿呼吸窘迫综合征(NRDS)中的应用效果.方法 选取2024 年 1 月至 2025 年 11 月广州市海珠区妇幼保健院收治的 110 例 NRDS 患儿,采用随机数字表法分为 2 组,各55 例.对照组接受常规护理,观察组加用主动风险干预联合早期俯卧位通气护理.比较 2 组患儿干预前、干预后24 h、48 h 的动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、氧合指数(OI),以及干预前、干预后2 d、7 d 的新生儿急性生理学评分—Ⅱ(SNAP-Ⅱ),并记录氧疗时间、无创机械通气时间、住院时间及并发症发生情况.结果 组间、时间、交互效应对 PaO2、OI、PaCO2 的影响均有统计学意义(P 均<0.05);干预后 24 h、48 h,观察组的 PaCO2均低于对照组,PaO2、OI 均高于对照组(P 均<0.05).组间、时间、交互效应SNAP-Ⅱ评分的影响均有统计学意义(P均<0.05).干预后 2 d、7 d,观察组的 SNAP-Ⅱ评分均低于对照组(P 均<0.05).观察组无创机械通气时间、住院时间相较于对照组均更短(P 均<0.05).观察组并发症总发生率相较于对照组更低(P<0.05).结论 主动风险干预联合早期俯卧位通气能有效改善 NRDS 患儿的氧合指数与通气功能,缩短临床治疗时间,降低并发症发生风险,临床综合效益显著.
Objective To explore the application effect of active risk intervention combined with early prone ventilation nursing in neonatal respiratory distress syndrome(NRDS).Methods A total of 110 neonates with NRDS admitted to Haizhu District Maternal and Child Health Hospital from January 2024 to November 2025 were selected and randomly divided into two groups using the random number table method,with 55 neonates in each group.The control group received routine nursing care,while the observation group received active risk intervention combined with early prone ventilation nursing in addition to routine care.Arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2),and oxygenation index(OI)were compared between the two groups before intervention,and at 24 and 48 hours after intervention.The Score for Neonatal Acute Physiology-Ⅱ(SNAP-Ⅱ)was compared before intervention and at 2 and 7 days after intervention.The duration of oxygen therapy,duration of non-invasive mechanical ventilation,length of hospital stay,and incidence of complications were also recorded.Results The effects of intergroup,time,and interaction on PaO2,OI,and PaCO2 were all statistically significant(P<0.05).At 24 and 48 hours after intervention,the observation group had lower PaCO2 levels and higher PaO2 and OI values than the control group(P<0.05).The effects of intergroup,time,and interaction on SNAP-Ⅱ scores were statistically significant(P<0.05).At 2 and 7 days after intervention,the SNAP-Ⅱ scores in the observation group were lower than those in the control group(P<0.05).The observation group had significantly shorter non-invasive mechanical ventilation time and length of hospital stay compared with the control group(P<0.05).The overall incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion Active risk intervention combined with early prone ventilation can effectively improve oxygenation index and ventilatory function in neonates with NRDS,shorten clinical treatment time,and reduce the risk of complications,demonstrating significant clinical comprehensive benefits.
林艳霞;胡笑群;黄清奇;张惠明
广州市海珠区妇幼保健院,广东 广州,510000广州市海珠区妇幼保健院,广东 广州,510000广州市海珠区妇幼保健院,广东 广州,510000广州市海珠区妇幼保健院,广东 广州,510000
医药卫生
新生儿呼吸窘迫综合征主动风险干预俯卧位通气血气分析指标氧合指数
neonatal respiratory distress syndromeactive risk interventionprone ventilationblood gas analysis indicatorsoxygenation index
《中西医结合护理（中英文）》 2026 (5)
87-91,5
评论