首页|期刊导航|中外医学研究|老年ST段抬高型急性心肌梗死患者PCI术后ST-T改变对短期预后的影响及发生MACE的危险因素分析

老年ST段抬高型急性心肌梗死患者PCI术后ST-T改变对短期预后的影响及发生MACE的危险因素分析OA

Effect of ST-T Changes on Short-term Prognosis and Risk Factor Analysis of MACE in Elderly Patients with STEMI After PCI

中文摘要英文摘要

目的:探讨老年ST段抬高型急性心肌梗死(STEMI)患者经皮冠状动脉介入治疗(PCI)后,心电图ST-T改变与短期预后的关联性,并分析术后发生主要不良心血管事件(MACE)的独立危险因素.方法:选取 2023 年 1 月—2025 年 12 月连云港市赣榆区人民医院收治的 200 例老年STEMI患者为研究对象,根据术后 24 h心电图ST-T变化特征,分为ST-T改变组(n=134)与ST-T未改变组(n=66).随访 6 个月,比较两组左心室功能及MACE的发生情况,并分析MACE的危险因素.结果:术后 6 个月,ST-T改变组左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、左心室射血分数(LVEF)指标均优于ST-T未改变组;ST-T改变组MACE发生率明显低于ST-T未改变组,以上差异均有统计学意义(P<0.05).经多因素logistic回归分析,ST-T未改变(OR=4.741)、年龄(OR=2.484)、合并糖尿病(OR=2.366)、术后TIMI血流≤Ⅱ级(OR=4.213)、总缺血时间(OR=3.509)、肌酐(OR=1.705)均是发生MACE的危险因素.结论:老年STEMI患者PCI术后ST-T未改变、高龄、合并糖尿病、术后TIMI血流≤Ⅱ级、总缺血时间延长及肌酐升高是短期MACE的独立危险因素.

Objective:To investigate the correlation between electrocardiographic ST-T changes and short-term prognosis in elderly patients with STEMI after PCI,and to analyze the independent risk factors for postoperative MACE.Method:A total of 200 elderly STEMI patients admitted to the hospital from January 2023 to December 2025 were enrolled as research subjects.According to the characteristics of electrocardiographic ST-T changes 24 hours after surgery,the patients were divided into the ST-T change group(n=134)and the ST-T non-change group(n=66).All patients were followed up for 6 months.Left ventricular function and the incidence of MACE were compared between the two groups,and the risk factors for MACE were analyzed.Result:At the 6-month follow-up,the LVEDD,LVESD,LVEF in the ST-T change group were significantly superior to those in the ST-T non-change group(P<0.05).The incidence of MACE in the ST-T change group was markedly lower than that in the ST-T non-change group(P<0.05).Multivariate logistic regression analysis revealed that ST-T non-change(OR=4.741),age(OR=2.484),complicated diabetes mellitus(OR=2.366),postoperative TIMI flow grade≤Ⅱ(OR=4.213),total ischemic time(OR=3.509)and serum creatinine level(OR=1.705)were independent risk factors for MACE.Conclusion:ST-T non-change,advanced age,complicated diabetes mellitus,postoperative TIMI flow grade≤Ⅱ,prolonged total ischemic time and elevated serum creatinine are independent risk factors for short-term MACE in elderly STEMI patients after PCI.

李达;张毅;谢军

连云港市赣榆区人民医院 江苏 连云港 222100连云港市赣榆区人民医院 江苏 连云港 222100连云港市赣榆区人民医院 江苏 连云港 222100

老年ST-T经皮冠状动脉介入术不良心血管事件

ElderlyST-TPCIMACEAdverse cardiovascular events

《中外医学研究》 2026 (13)

12-16,21,6

江苏省连云港市科协项目(Lkxyb24365)

10.14033/j.cnki.cfmr.2026.13.003

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