内镜下多点套扎不同点数治疗Ⅱ~Ⅲ度内痔的临床效果分析OA
Analysis of the clinical effect of endoscopic multi-band ligation with different points in the treatment of grade Ⅱ-Ⅲ internal hemorrhoids
目的 探讨不同点数对Ⅱ~Ⅲ度内痔内镜下套扎术(endoscopic rubber band ligation,ERBL)治疗效果与不良反应的影响.方法 选取2020年6月至2024年12月于梅州市人民医院接受ERBL治疗的内痔患者554例,根据单次套扎点数将其分为A组(4~5环)和B组(6~7环);因内痔分度分布差异显著,采用分层分析消除混杂,分别在Ⅱ度、Ⅲ度内痔亚组内对比两组疗效及术后不良反应发生情况,采用多因素Logistic回归分析影响疗效和术后不良反应的独立危险因素.结果 总体及分层分析均显示A、B两组的治疗总有效率、术后出血发生率比较差异均无统计学意义(P>0.05);B组患者术后1h、24h、48h的肛门疼痛视觉模拟评分法评分及肛门坠胀、排便困难、尿潴留发生率均显著高于A组(P<0.05).多因素Logistic回归分析结果显示,套扎点数是Ⅱ度、Ⅲ度内痔患者术后疼痛、肛门坠胀、尿潴留发生的独立危险因素(P<0.05).结论 ERBL治疗Ⅱ~Ⅲ度内痔安全有效.同一分度内痔患者增加套扎点数未提升治疗效果,但显著增加术后疼痛、肛门坠胀、尿潴留等不良反应的发生风险.
Objective To explore the influence of the therapeutic effect and adverse reactions of endoscopic rubber band ligation(ERBL)with different ligation bands for grade Ⅱ-Ⅲ internal hemorrhoids.Methods A total of 554 patients with internal hemorrhoids who received ERBL treatment at Meizhou People's Hospital from June 2020 to December 2024 were selected and divided into group A(4-5 bands)and group B(6-7 bands)based on the number of ligation bands.Due to significant differences in the distribution of internal hemorrhoid grades,stratified analysis was performed to control for confounding.Efficacy and postoperative adverse reactions were compared within the grade Ⅱ and grade Ⅲ subgroups.Multivariate Logistic regression analysis was performed to determine the independent risk factors affecting treatment efficacy and postoperative adverse reactions.Results Both overall and stratified analyses showed no statistically significant difference in total efficacy rates or incidence of postoperative bleeding between group A and group B(P>0.05).Visual analogue scale scores for anal pain at 1h,24h,and 48h after surgery and the incidences of anal distension,defecation difficulty and urinary retention in group B were significantly higher than those in group A(P<0.05).Multivariate Logistic regression indicated that the number of ligation bands was an independent risk factor for postoperative pain,anal distention,and urinary retention in both grade Ⅱ and grade Ⅲ internal hemorrhoid patients(P<0.05).Conclusion ERBL is safe and effective in the treatment of grade Ⅱ to Ⅲ internal hemorrhoids.For patients with internal hemorrhoids of the same grade,increasing the number of ligation bands does not improve the therapeutic effect,but it significantly increases the risk of adverse reactions such as postoperative pain,anal distension,and urinary retention.
黄思婷;陈奕金;胡丽芬;郭学敏;卢佳莹
梅州市人民医院消化内三科,广东 梅州 514031梅州市人民医院消化内三科,广东 梅州 514031梅州市人民医院消化内三科,广东 梅州 514031梅州市人民医院科研实验中心,广东 梅州 514031梅州市人民医院消化内三科,广东 梅州 514031
医药卫生
内痔多点套扎套扎点数疗效不良反应
Internal hemorrhoidMulti-band ligationNumber of ligation bandsEfficacyAdverse reaction
《中国现代医生》 2026 (16)
18-21,37,5
广东省梅州市医药卫生科研项目(2024-B-9)
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