罗哌卡因区域阻滞多模式镇痛应用于腹腔镜子宫切除术后的效果OA
Effects of Ropivacaine Regional Block-Based Multimodal Analgesia after Laparoscopic Hysterectomy
目的:探讨罗哌卡因区域阻滞多模式镇痛方案在腹腔镜子宫切除术后患者中的应用效果.方法:选取 2023 年1月~2024年12 月于本院拟行腹腔镜子宫切除术的 90 例患者,按照随机数字表法分为对照组和观察组,每组45 例.对照组采用常规术后镇痛方案,观察组在对照组基础上实施术后罗哌卡因区域阻滞多模式镇痛.比较两组患者术后不同时间点静息和运动状态下的疼痛程度[采用数字分级评分法(NRS)评价]、术后恢复情况、镇痛药物使用情况及不良反应发生情况.结果:术后 6、12、24、48 h,观察组静息及运动状态下的NRS 评分均低于对照组(P<0.05).与对照组相比,观察组术后首次下床活动、术后首次排气及住院所需时间更短(P<0.05);术后48 h内镇痛泵按压次数更少,首次按压镇痛泵时间更晚,补救镇痛药物使用率更低(P<0.05).观察组不良反应总发生率(6.67%)低于对照组(24.44%,P<0.05).结论:基于罗哌卡因区域阻滞的多模式镇痛方案规范化应用于腹腔镜子宫切除术,可有效缓解术后疼痛,促进术后恢复,减少术后对阿片类药物的镇痛需求并降低不良反应发生风险,为围术期镇痛管理安全有效的实施提供参考.
Objective:To investigate the effect of a ropivacaine regional block-based multimodal analgesia regimen in patients after laparoscopic hysterectomy.Methods:A total of 90 patients scheduled to undergo laparoscopic hysterectomy at our hospital from January 2023 to December 2024 were selected and randomized by the random number table method into a control group and an observation group,with 45 patients in each group.The control group received a conventional postoperative analgesia regimen,whereas the observation group received postoperative ropivacaine regional block-based multimodal analgesia in addition to the treatment given to the control group.Pain intensity at rest and during movement at different postoperative time points[assessed using the Numerical Rating Scale(NRS)],postoperative recovery,analgesic medication use,and adverse reactions were compared between the two groups.Results:At 6,12,24,and 48 h after surgery,NRS scores at rest and during movement were lower in the observation group than in the control group(P<0.05).Compared with the control group,the observation group had shorter times to first ambulation and first flatus after surgery and a shorter hospital stay(P<0.05).Within 48 h after surgery,the observation group had fewer analgesic pump presses,a later time to first analgesic pump press,and a lower rate of rescue analgesic use(P<0.05).The overall incidence of adverse reactions was lower in the observation group than in the control group(6.67%vs 24.44%,P<0.05).Conclusion:Standardized application of a ropivacaine regional block-based multimodal analgesia regimen for laparoscopic hysterectomy can effectively relieve postoperative pain,promote postoperative recovery,reduce postoperative opioid analgesic requirements,and lower the risk of adverse reactions,providing a reference for the safe and effective implementation of perioperative analgesia management.
李姣;刘洋;张睿
南阳南石医院麻醉与围术期医学科,南阳 473000南阳南石医院麻醉与围术期医学科,南阳 473000南阳南石医院麻醉与围术期医学科,南阳 473000
医药卫生
罗哌卡因区域阻滞多模式镇痛腹腔镜子宫切除术镇痛
ropivacaineregional blockmultimodal analgesialaparoscopic hysterectomyanalgesia
《中国合理用药探索》 2026 (6)
89-95,7
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