HBx-mediated GPT2 suppression promotes liver cancer development by downregulating ADH1AOA
HBx-mediated GPT2 suppression promotes liver cancer development by downregulating ADH1A
Hongjuan You;Delong Kong;Xiucheng Pan;Xiaocui Li;Suping Qin;Kuiyang Zheng;Chen Li;Renxian Tang;Fanyun Kong;Xing Wang;Ruyu Liu;Yuxin Wang;Huanyang Zhang;Lihong Ma;Ensi Bao;Yujie Zhong;Xiangye Liu
Jiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaDepartment of Infectious Diseases,The Affiliated Hospital of Xuzhou Medical University,Xuzhou 221006,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,China||National Demonstration Center for Experimental Basic Medical Sciences Education,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,China||National Demonstration Center for Experimental Basic Medical Sciences Education,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,China||Department of Clinical Laboratory,Heping Hospital Affiliated to Changzhi Medical College,Changzhi 046000,ChinaDepartment of Hepatology Division,Beijing Ditan Hospital Affiliated to Capital Medical University Xuzhou Hospital and Xuzhou Seventh People's Hospital,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,ChinaJiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,China
Liver cancerHBxGPT2ADH1ACBLLSD1
Liver cancerHBxGPT2ADH1ACBLLSD1
《癌症生物学与医学（英文版）》 2026 (6)
888-909,22
This study was supported by the Qing Lan Project of Jiangsu Province,the National Natural Science Foundation of China(Grant No.82372245),and a Starting Grant for Talents of Xuzhou Medical University(Grant No.RC20552309).
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