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通元针法治疗带状疱疹后神经痛:随机对照试验OA

Tongyuan acupuncture for postherpetic neuralgia:a randomized controlled trial

中文摘要英文摘要

目的:观察通元针法治疗带状疱疹后神经痛(PHN)的临床有效性.方法:将106 例PHN 患者随机分为通元电针组(53 例,脱落 3 例)和普通电针组(53 例,脱落 4 例、剔除 2 例).通元电针组穴取百会、印堂、水沟、气海、关元、阿是穴及双侧心俞、膈俞、肝俞、脾俞、天枢,选择 5~6 组腧穴连接电针治疗仪;普通电针组穴取阿是穴及患区相关神经节段的夹脊穴,患区相关神经节段夹脊穴及阿是穴连接电针治疗仪.两组均选择疏密波,频率2 Hz/100 Hz,电流2 mA,留针 30 min,每日 1 次,5次为一疗程,疗程间休息2 d,共治疗 4个疗程.分别于治疗前、治疗 2 周后、治疗 4 周后观察两组患者简化 McGill 疼痛问卷(SF-MPQ)评分[包括疼痛分级指数(PRI)评分、视觉模拟量表(VAS)评分、现有疼痛强度评定(PPI)评分],于治疗前、治疗4周后观察两组患者匹兹堡睡眠质量指数(PSQI)评分、汉密尔顿焦虑量表(HAMA)评分、汉密尔顿抑郁量表(HAMD)评分,于治疗后评定临床疗效,并于治疗结束后 3 个月随访患者疼痛复发情况.结果:与治疗前比较,两组患者治疗2、4周后,SF-MPQ各分项评分及总分均降低(P<0.05),且治疗 4周后评分低于治疗2周后评分(P<0.05);治疗2周后通元电针组VAS、PPI评分及 SF-MPQ总分低于普通电针组(P<0.05),治疗 4周后通元电针组SF-MPQ各分项评分及总分低于普通电针组(P<0.05).两组患者治疗后PSQI、HAMA、HAMD评分低于治疗前(P<0.05);治疗后通元电针组 PSQI、HAMA、HAMD 评分低于普通电针组(P<0.05).通元电针组总有效率、显效率分别为90.0%(45/50)、72.0%(36/50),均高于普通电针组的74.5%(35/47)和44.7%(21/47).治疗结束后3 个月随访,通元电针组疼痛复发率为 2.2%(1/45),低于普通电针组的 17.1%(6/35,P<0.05).结论:通元针法可缓解 PHN患者疼痛、改善睡眠障碍及情绪共病,且近期及远期疗效优于普通电针治疗.

Objective To observe the clinical efficacy of Tongyuan acupuncture in treatment of postherpetic neuralgia(PHN).Methods A total of 106 patients with PHN were randomly divided into a Tongyuan electroacupuncture group(53 cases,3 cases dropped out)and a conventional electroacupuncture group(53 cases,4 cases dropped out,2 cases were eliminated).In the Tongyuan electroacupuncture group,Baihui(GV20),Yintang(GV24+),Shuigou(GV26),Qihai(CV6),Guanyuan(CV4),ashi points and bilateral Xinshu(BL15),Geshu(BL17),Ganshu(BL18),Pishu(BL20),Tianshu(ST25)were selected,and 5 to 6 pairs of acupoints were selected to connect the electroacupuncture therapeutic apparatus;in the conventional electroacupuncture group,ashi points and Jiaji points(EX-B2)of the relevant ganglion segments in the affected area were selected,and Jiaji points(EX-B2)and ashi points were connected to the electroacupuncture therapeutic apparatus.In both groups,dense-disperse waves were selected at a frequency of 2 Hz/100 Hz and a current of 2 mA.The needles were retained for 30 min per session,once daily.Five sessions constituted one treatment course,with a 2-day interval between courses.A total of four treatment courses were administered.The simplified McGill pain questionnaire(SF-MPQ)score(including the pain rating index[PRI]score,visual analogue scale[VAS]score,and present pain intensity[PPI]score)of both groups were observed before treatment,after 2 weeks of treatment,and after 4 weeks of treatment.The Pittsburgh sleep quality index(PSQI)score,Hamilton anxiety scale(HAMA)score,and Hamilton depression scale(HAMD)score of both groups were observed before treatment and after 4 weeks of treatment.Clinical efficacy was evaluated after treatment,and pain recurrence was followed up at 3 months after treatment completion.Results Compared with before treatment,the sub-scores and total scores of the SF-MPQ in both groups decreased after 2 and 4 weeks of treatment(P<0.05),and the scores after 4 weeks of treatment were lower than those after 2 weeks of treatment(P<0.05).After 2 weeks of treatment,the scores of VAS and PPI,and the total score of SF-MPQ in the Tongyuan electroacupuncture group were lower than those in the conventional electroacupuncture group(P<0.05).After 4 weeks of treatment,all sub-scores and total score of the SF-MPQ in the Tongyuan electroacupuncture group were lower than those in the conventional electroacupuncture group(P<0.05).After treatment,the PSQI,HAMA,and HAMD scores in both groups were lower than those before treatment(P<0.05);the PSQI,HAMA,and HAMD scores in the Tongyuan electroacupuncture group were lower than those in the conventional electroacupuncture group(P<0.05).The total effective rate and marked effective rate in the Tongyuan electroacupuncture group were 90.0%(45/50)and 72.0%(36/50),respectively,both higher than those in the conventional electroacupuncture group(74.5%[35/47]and 44.7%[21/47],P<0.05).During follow-up,the pain recurrence rate in the Tongyuan electroacupuncture group was 2.2%(1/45),which was lower than that in the conventional electroacupuncture group(17.1%[6/35],P<0.05).Conclusion Tongyuan acupuncture can alleviate pain,improve sleep disturbances,and ameliorate emotional comorbidities in patients with PHN,and its short-term and long-term efficacy is superior to that of conventional electroacupuncture.

张洁;程孝顶;唐文龙;曲善忠;彭丽;严旭洪;倪瑶;路永红;尹斌

四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017四川大学华西临床医学院,四川大学附属成都市第二人民医院,成都市第二人民医院,成都 610017

带状疱疹后神经痛通元针法电针随机对照试验

postherpetic neuralgiaTongyuan acupunctureelectroacupuncturerandomized controlled trial(RCT)

《中国针灸》 2026 (7)

1068-1074,7

四川省中医药管理局课题项目:2023MS526

10.13703/j.0255-2930.20250518-k0002

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