首页|期刊导航|中国医学工程|增生性糖尿病视网膜病变PPV术后视力恢复的影响因素分析

增生性糖尿病视网膜病变PPV术后视力恢复的影响因素分析OA

Factors influencing visual recovery after pars plana vitrectomy for proliferative diabetic retinopathy

中文摘要英文摘要

目的 分析增生性糖尿病视网膜病变(PDR)微创玻璃体切割术(PPV)术后视力恢复的影响因素.方法 选取2023年3月至2025年3月开封市中心医院接受PPV手术治疗的PDR患者212例,根据术后3个月视力恢复情况将患者分为良好组(134例)和不良组(78例).收集患者基线资料,分析影响PDR患者PPV术后视力恢复的独立危险因素及预测价值.结果 良好组糖化血红蛋白(HbA1c)、术前最佳矫正视力(BCVA)(logMAR)值低于不良组,合并糖尿病肾病、黄斑区视网膜脱离、虹膜新生血管、填充物类型为硅油的患者占比均低于不良组(P<0.05);多因素Logistic回归分析显示,HbA1c、术前BCVA、合并糖尿病肾病、黄斑区视网膜脱离、虹膜新生血管、填充物类型为硅油是影响PDR患者PPV术后视力恢复的独立危险因素(P<0.05);经受试者操作特征(ROC)曲线分析证实,HbA1c、术前BCVA水平可用于预测PDR患者PPV术后视力恢复,曲线下面积分别为0.884和0.801(P<0.05).结论 HbA1c、术前BCVA、合并糖尿病肾病、黄斑区视网膜脱离、虹膜新生血管、填充物类型为硅油是影响PDR患者PPV术后视力恢复的独立危险因素.

[Objective]To analyze the factors influencing visual recovery following microincision pars plana vitrectomy(PPV)in patients with proliferative diabetic retinopathy(PDR).[Methods]A total of 212 PDR patients who underwent PPV surgery in Kaifeng Central Hospital from March 2023 to March 2025 were enrolled.Based on visual acuity 3 months postoperatively,patients were divided into a good visual recovery group(n=134)and a poor visual recovery group(n=78).Baseline data were collected.Independent risk factors influencing postoperative visual recovery and their predictive value were analyzed.[Results]The good recovery group exhibited significantly lower HbA1c levels and preoperative best corrected visual acuity(BCVA)compared with the poor recovery group.Furthermore,the proportions of patients with concurrent diabetic nephropathy,macular retinal detachment,iris neovascularization,or silicone oil tamponade were significantly lower in the good recovery group(P<0.05).Multivariate logistic regression analysis showed that HbA1c,preoperative BCVA,diabetic nephropathy,macular retinal detachment,iris neovascularization,and silicone oil filling type were independent risk factors affecting the visual recovery of PDR patients after PPV(P<0.05).Receiver operating characteristic(ROC)curve analysis confirmed that HbA1c and preoperative BCVA levels can be used to predict the visual recovery of PDR patients after PPV,and the areas under the curve were 0.884 and 0.801,respectively(P<0.05).[Conclusion]HbA1c level,preoperative BCVA,concurrent diabetic nephropathy,macular retinal detachment,iris neovascularization,and the use of silicone oil tamponade are independent risk factors influencing visual recovery after PPV in PDR patients.

张晓丽;齐坤英;侯立亭;郭洋

开封市中心医院(开封市眼病医院、开封市白内障与近视重点实验室)眼科,河南 开封 475000开封市中心医院(开封市眼病医院、开封市白内障与近视重点实验室)眼科,河南 开封 475000开封市中心医院(开封市眼病医院、开封市白内障与近视重点实验室)眼科,河南 开封 475000开封市中心医院(开封市眼病医院、开封市白内障与近视重点实验室)眼科,河南 开封 475000

医药卫生

增生性糖尿病视网膜病变微创玻璃体切割术视力恢复危险因素预测价值

proliferative diabetic retinopathypars plana vitrectomyvisual recoveryrisk factorspredictive value

《中国医学工程》 2026 (5)

70-75,6

10.19338/j.issn.1672-2019.2026.05.013

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