剖宫产术后瘢痕妊娠患者手术治疗与再次妊娠结局分析OA
Surgical management and subsequent pregnancy outcomes in patients with cesarean scar pregnancy:a clinical analysis
目的 探讨不同分型剖宫产瘢痕妊娠(caesarean scar pregnancy,CSP)的临床特点、手术治疗方法的优劣,以及各种治疗方式对术后妊娠结局的影响.方法 回顾性分析2016年1月1日至2022年12月31日中国医科大学附属盛京医院943例CSP手术患者的临床资料,按2016年中华医学会CSP分型标准分为Ⅰ型、Ⅱ型、Ⅲ型(包块型/非包块型).分析不同组间临床差异、手术效果优劣和术中出血等高危因素.随访获取患者再次妊娠结局,应用统计学方法描述患者临床变量差别.结果 纳入的943例CSP手术患者,Ⅰ型363例(38.5%),Ⅱ型387例(41.1%),非包块Ⅲ型124例(13.1%),包块Ⅲ型69例(7.3%).各分型停经时间、妊娠囊最大径线等差异有统计学意义;不同术式的术中出血量、住院费有差异,整体成功率较高.非包块Ⅲ型患者中,停经时间是宫腔镜手术切除(TCR)±吸宫术转为其他手术的独立影响因素,妊娠囊最大径线等是术中出血较多的危险因素.随访78例再妊娠患者,22例为瘢痕妊娠,术中是否修补瘢痕肌层与再妊娠结局相关,未修补者瘢痕妊娠风险更高.结论 TCR±吸宫术适用于Ⅰ型、Ⅱ型CSP;非包块Ⅲ型CSP需谨慎选择术式.术中修补瘢痕肌层有助于改善再次妊娠结局.
Objective To investigate the clinical characteristics of different types of Caesarean scar pregnancy(CSP),compare the efficacy of corresponding surgical treatment approaches,and assess the impact of various treatments on subsequent pregnancy outcomes.Methods A total of 943 CSP patients undergoing surgery at Shengjing Hospital of CMU from Jan.1,2016 to Dec.31,2022 were included and their clinical data were retrospectively analyzed.Patients were classified by 2016 CM A criteria into types Ⅰ,Ⅱ and Ⅲ(mass/non-mass).Clinical differences,surgical outcomes,and risk factors for intraoperative bleeding were compared among the groups.Follow-up was used to assess the subsequent pregnancy outcomes.Statistical methods were adopted to describe the differences in clinical variables.Results Among the 943 CSP patients,type Ⅰ accounted for 38.5%(363 cases),type Ⅱ 41.1%(387 cases),non-mass type Ⅲ 13.1%(124 cases),and mass type Ⅲ 7.3%(69 cases).Significant differences were observed in amenorrhea duration and maximum gestational sac diameter among different types.There were differences in intraoperative blood loss and hospitalization costs among different surgical approaches,with a high overall success rate.In non-mass type Ⅲ patients,amenorrhea duration was an independent influencing factor for the change from TCR±suction curettage to other surgical approaches,while the largest gestational sac diameter was a risk factor for increased blood loss during surgery.Follow-up of 78 patients with subsequent pregnancies revealed 22 cases of CSP.Intraoperative repair of scar myometrium was associated with subsequent pregnancy outcomes,and those without repair had a higher risk.Conclusions TCR±suction curettage is suitable for type Ⅰ and type Ⅱ CSP;for non-mass type Ⅲ CSP,surgical approach should be chosen with caution.IntIraoperative repair of scar myometrium helps to improve subsequent pregnancy outcomes.
耿丹波;王敏;张玉倩;刘同庆;何润泽;刘宇曦;任波;杨烨;张晓巍;芮炳杰
中国医科大学附属盛京医院妇产科,辽宁沈阳 110004中国医科大学附属盛京医院妇产科,辽宁沈阳 110004山东省临清市人民医院妇科,山东临清 252600中国医科大学附属盛京医院妇产科,辽宁沈阳 110004中国医科大学附属盛京医院妇产科,辽宁沈阳 110004中国医科大学附属盛京医院妇产科,辽宁沈阳 110004锦州市妇婴医院(锦州市妇幼保健院)妇产科,辽宁锦州 121000锦州市妇婴医院(锦州市妇幼保健院)妇产科,辽宁锦州 121000锦州医科大学附属第一医院妇产科,辽宁锦州 121000抚顺市中心医院妇产科,辽宁抚顺 113006
医药卫生
剖宫产瘢痕妊娠子宫动脉栓塞术经腹/宫腹联合手术再次妊娠结局
caesarean scar pregnancyuterine artery embolizationtransabdominal/combined laparotomic-hysteroscopic surgerysubsequent pregnancy outcome
《中国实用妇科与产科杂志》 2026 (6)
646-650,5
国家重点研发计划(2018YFC1004203) National Key Research and Development Program of China(2018YFC1004203)
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