孕产妇脓毒症的集束化管理OA

Maternal sepsis is a severe infectious condition occurring during pregnancy and the puerperium that poses a significant threat to both maternal and fetal health.Glob-ally,it remains one of the leading causes of maternal mor-tality.The unique physiological changes associated with pregnancy may obscure the early manifestations of sepsis,thereby contributing to delayed clinical diagnosis and un-timely intervention.Bundle management,which integrates a series of evidence-based standardized interventions,pro-vides a systematic framework for the standardized diagnosis and treatment of obstetric sepsis.Upon early identification of sepsis,the bundle management of obstetric sepsis should be initiated promptly.This includes the measures concerning lactate measurement,microbiological cultures,administration of broad-spectrum antibiotics,fluid resusci-tation,and the use of vasopressors,with careful consider-ation of obstetric-specific adaptations.Particular emphasis should be placed on the timeliness of antibiotic therapy and adherence to the principle of de-escalation.Sepsis itself is not an indication for termination of pregnancy;in most cas-es,pregnancy can be safely continued once the underlying cause of infection is identified and appropriately managed.