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家畜乳腺脂质合成与转运的研究进展OA

Advances in lipid synthesis and transport in livestock mammary glands

中文摘要英文摘要

乳腺上皮细胞在家畜泌乳过程中扮演着核心角色,负责合成并分泌乳汁.乳汁中的脂质对新生动物的生长发育至关重要,也是评价乳营养价值的重要指标.乳脂主要由甘油三酯组成,其合成和分泌过程受到多种因素的精细调控.合成后的甘油三酯等乳脂被包装成脂滴,通过乳腺上皮细胞分泌到腺泡腔中,形成乳汁.这一过程涉及脂肪酸的合成、甘油骨架的形成以及甘油三酯的合成,而且是一个动态、多层次调控的过程.此外,乳腺上皮细胞的脂质合成与转运涉及多种生化途径和细胞机制,包括激素、营养物质、基因和信号转导通路等.这些因素共同作用,对乳脂的合成和分泌进行精细调控.本文综述了近年来乳腺上皮细胞脂质合成与转运的研究进展,深入理解这些分子机制对于提高乳产品质量以及改善乳业生产具有重要的科学和实践意义.未来需进一步探索这些调控因素之间的相互作用及其对乳腺上皮细胞脂质代谢的影响,为乳产品质量的提升提供理论参考.

Mammary epithelial cells play a central role in the lactation process of livestock,responsible for synthesizing and secreting milk.Lipids in milk are crucial for the growth and development of newborn animals and are also important indicators for evaluating the nutritional value of milk.Milk fat is mainly composed of triglycerides,and its synthesis and secretion processes are finely regulated by various factors.The synthesized triglycerides and other milk fat are packaged into lipid droplets and secreted into the acinar cavity bymammary epithelial cells to form milk.This process not only involves the synthesis of fatty acids,glycerol skeleton and triglycerides,but also is a dynamic and multi-level regulated process.In addition,lipid synthesis and transport in mammary epithelial cells involve multiple biochemical pathways and cellular regulatory mechanisms,including hormones,nutrients,genes,and signal transduction pathways.These factors collectively modulate the synthesis and secretion of milk fat through a fine-tuned regulatory mechanism.This article reviewed the research progress on lipid transport and synthesis in mammary epithelial cells in recent years.A deep understanding of these molecular mechanisms is of great scientific and practical significance for improving the quality of dairy products and enhancing dairy production.In future research,the interactions between these regulatory factors and their influences on lipid metabolism in mammary epithelial cells need to explore,which will provide theoretical values for improving the quality of dairy products.

刘新宇;王欢;卢冬;肖文哲;周小玲

塔里木大学动物科学与技术学院,新疆生产建设兵团塔里木畜牧科技重点实验室,农业农村部环塔里木畜草资源利用重点实验室,新疆 阿拉尔 843300阿拉尔新农乳业有限责任公司,新疆 阿拉尔 843300塔里木大学动物科学与技术学院,新疆生产建设兵团塔里木畜牧科技重点实验室,农业农村部环塔里木畜草资源利用重点实验室,新疆 阿拉尔 843300塔里木大学动物科学与技术学院,新疆生产建设兵团塔里木畜牧科技重点实验室,农业农村部环塔里木畜草资源利用重点实验室,新疆 阿拉尔 843300塔里木大学动物科学与技术学院,新疆生产建设兵团塔里木畜牧科技重点实验室,农业农村部环塔里木畜草资源利用重点实验室,新疆 阿拉尔 843300

农业科技

乳腺上皮细胞甘油三酯脂质合成脂质转运

breast epithelial cellstriglycerideslipid synthesislipid transport

《中国饲料》 2026 (11)

1-6,6

兵团财政科技计划项目(2022BB001)国家自然科学基金(32260844)"天山英才"培养计划"三农"骨干人才培养项目

10.15906/j.cnki.cn11-2975/s.2025040051-05

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