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子宫内膜异位症疼痛管理相关指南和专家共识的系统评价OA

A Systematic Review of Guidelines and Expert Consensus Related to Pain Management in Endometriosis

中文摘要英文摘要

背景 随着对子宫内膜异位症疼痛管理认识的深入,相关国内外的指南/专家共识逐渐增多,为临床实践提供了重要的指导和参考,但其质量参差不齐,需进行系统评价以指导临床实践.目的 系统评价子宫内膜异位症疼痛管理相关指南/专家共识的质量,为制订疼痛管理方案提供依据.方法 计算机检索中国知网、中国生物医学文献数据库、万方数据知识服务平台、维普网、PubMed、Embase、Cochrane Library、Web of Science、CINAHL数据库、Guideline Central、国际指南协作网(GIN)以及美国妇产科医学会(ACOG)、英国国家卫生与临床优化研究所(NICE)、苏格兰校际指南网(SIGN)、WHO、国际疼痛研究协会(IASP)、美国疼痛协会(APS)、大不列颠疼痛协会(BPS)官网及其他途径获取发布的子宫内膜异位症疼痛管理相关指南,检索时限为建库至 2024-11-12.运用临床指南研究与评价工具Ⅱ(AGREE Ⅱ)对子宫内膜异位症疼痛管理相关指南/专家共识进行质量评价,并对相关推荐意见进行汇总.结果 最终纳入 15 部指南/专家共识,其中 9 部为指南,6 部为专家共识;7 部来自中国,8 部来自国外;发布时间为 2018-2024 年.AGREE Ⅱ的 6 个领域中,15 部指南/专家共识平均得分分别为:范围和目的 83.15%、参与人员 71.11%、严谨性 44.79%、清晰性 65.74%、应用性 35.55%、独立性 87.78%.纳入的 15 部指南/专家共识中,A 级推荐 1 部,B 级推荐 14 部.从 15 部指南/专家共识中共提取 33 条子宫内膜异位症疼痛管理相关推荐意见,涉及疼痛管理总原则、疼痛评估、药物管理、手术管理、非药物/手术管理、健康教育 6 个方面.结论 纳入的指南/专家共识质量处于中等水平,为临床实践提供了参考依据,但在严谨性、应用性领域仍有待进一步改进.

Background As the understanding of pain management in endometriosis deepens,an increasing number of related guidelines and expert consensus have emerged both domestically and internationally,providing significant guidance and reference for clinical practice.However,the quality of these guidelines and expert consensuses is inconsistent,necessitating a systematic review to guide clinical practice.Objective To systematically evaluate the quality of guidelines and expert consensus related to pain management in endometriosis,thereby providing an evidence base for the development of pain management protocols.Methods Evidence-based guidelines involving recommendations for pain management in endometriosis were searched in CNKI,SinoMed,Wanfang Data,VIP,PubMed,Embase,Cochrane Library,Web of Science,CINAHL,Guideline Central,GIN,as well as the official websites of ACOG,NICE,SIGN,WHO,IASP,APS and BPS,and other sources from inception to 12 November,2024.AGREEⅡ was utilized to assess the quality of guidelines and expert consensus related to pain management in endometriosis,and relevant recommendations were summarized.Results A total of 15 guidelines/expert consensus were ultimately included,of which 9 were guidelines and 6 were expert consensuses.7 guidelines/expert consensus were from China,and 8 were from abroad.The publication dates ranged from 2018 to 2024.Among the 6 domains of AGREE Ⅱ,the average scores of the 15 guidelines/expert consensuses were as follows:scope and purpose(83.15%),stakeholder involvement(71.11%),rigor of development(44.79%),clarity of presentation(65.74%),applicability(35.55%),editorial independence(87.78%).33 recommendations were extracted and summarized from 15 guidelines/expert consensus,involving 6 domains,namely general principles of pain management,pain assessment,medication management,surgical management,non-pharmacologic/surgical management,health education.Conclusion The quality of the included guideli`nes/expert consensus is at a moderate level and provides a reference point for clinical practice,but further improvement is needed in the areas of the rigour of development and applicability.

谢婉;涂旭莲;吴丽萍;刘霞;李晓燕;冷明月;杨雪青;李莉

100144 北京市,中国医学科学院北京协和医学院护理学院100730 北京市,女性健康与妇产疾病国家临床医学研究中心 中国医学科学院北京协和医学院 北京协和医院妇产科100144 北京市,中国医学科学院北京协和医学院护理学院100730 北京市,女性健康与妇产疾病国家临床医学研究中心 中国医学科学院北京协和医学院 北京协和医院妇产科100730 北京市,女性健康与妇产疾病国家临床医学研究中心 中国医学科学院北京协和医学院 北京协和医院妇产科100730 北京市,女性健康与妇产疾病国家临床医学研究中心 中国医学科学院北京协和医学院 北京协和医院妇产科100730 北京市,女性健康与妇产疾病国家临床医学研究中心 中国医学科学院北京协和医学院 北京协和医院妇产科100730 北京市,女性健康与妇产疾病国家临床医学研究中心 中国医学科学院北京协和医学院 北京协和医院妇产科

医药卫生

子宫内膜异位症疼痛管理指南专家共识质量评价

EndometriosisPainManagementGuidelineExpert consensusQuality appraisal

《中国全科医学》 2026 (23)

3351-3358,8

国家重点研发计划(2022YFC2704000)中央高水平医院临床科研业务费资助(2022-PUMCH-B-085)2025年度北京协和医学院护理学院科研项目(PUMCSON202508)

10.12114/j.issn.1007-9572.2025.0016

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