E3泛素连接酶调控园艺作物非生物胁迫响应的分子机制及展望OA
Molecular mechanisms and prospects of E3 ubiquitin ligases regulating abiotic stress responses in horticultural crops
园艺作物在日常饮食和国民经济中占据重要地位,然而其生长发育经常遭受非生物胁迫威胁,导致产量与品质受损.E3泛素连接酶作为泛素-蛋白酶体系统(UPS)的核心调控因子,通过特异性识别靶蛋白并介导泛素共价修饰,精准调控蛋白质降解或功能激活,在园艺作物应对非生物胁迫中充当重要角色.本研究系统综述了 E3泛素连接酶的分类特征、催化机制及其在非生物胁迫响应中的分子机制,重点探讨其在干旱、高盐及极端温度胁迫下的角色,总结了 E3泛素连接酶通过脱落酸(ABA)和茉莉酸(JA)等激素途径参与胁迫响应的分子网络.同时,提出基于E3泛素连接酶的分子设计育种策略和未来研究方向,为园艺作物抗逆遗传改良提供新的理论依据与技术路径.
Horticultural crops play a vital role in daily diets and national economies.However,their growth and development are frequently threatened by abiotic stresses,leading to reduced yield and compromised quality.As core regulators of the ubiquitin-proteasome system(UPS),E3 ubiquitin ligases precisely control protein degradation or functional activation by specifically recognizing target proteins and mediating covalent ubiquitination modifications,and plays a vital role in the response of horticultural crops to abiotic stresses.This study systematically summarizes the classification characteristics,catalytic mechanisms,and molecular roles of E3 ubiquitin ligases in abiotic stress responses,with a focus on their regulatory functions under drought,high salinity,and extreme temperature stresses.Meanwhile,this paper reveals the molecular network of E3 ubiquitin ligase participating in stress response through hormone pathways such as abscisic acid(ABA)and jasmonic acid(JA).In addition,this study proposes molecular design breeding strategies based on E3 ubiquitin ligases and outlines future research directions,aiming to provide new theoretical foundations and technical approaches for the genetic improvement of stress tolerance in horticultural crops.
陈萃;翁年东;田鑫;张震
宁夏大学葡萄酒与园艺学院,银川 750021宁夏大学葡萄酒与园艺学院,银川 750021宁夏大学葡萄酒与园艺学院,银川 750021宁夏大学葡萄酒与园艺学院,银川 750021
农业科技
E3泛素连接酶园艺作物非生物胁迫泛素化修饰激素信号遗传改良
E3 ubiquitin ligasehorticultural cropsabiotic stressubiquitination modificationhormone signalinggenetic improvement
《中国农业大学学报》 2026 (7)
85-94,10
国家自然科学基金项目(32502668)宁夏自然科学基金项目(2025AAC050041)
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