首页|期刊导航|中风与神经疾病杂志|原发免疫性血小板减少症后短暂性全面性遗忘症1例报告并文献综述

原发免疫性血小板减少症后短暂性全面性遗忘症1例报告并文献综述OA

Transient global amnesia after primary immune thrombocytopenia:A case report and literature review

中文摘要英文摘要

原发免疫性血小板减少症(ITP)是一种以免疫介导的血小板破坏为特征的血液系统疾病,临床常表现为皮肤黏膜出血等症状,而以短暂性全面性遗忘症(TGA)为首发表现者极为罕见.本文报道1例以短暂性全面性遗忘症为首发表现的原发免疫性血小板减少症患者.患者为老年女性,既往体健,因突发头晕伴记忆障碍入院,表现为发病过程记忆受损、反复提问.头部MRI提示基底节区腔隙性脑梗死.入院后实验室检查发现血小板显著减少,进一步完善相关检查后确诊为ITP.经规范治疗后患者症状缓解,未再出现类似发作.本病例提示,TGA可作为ITP的罕见首发表现,临床在诊治突发记忆障碍的患者时,应重视血液学异常的筛查,以避免漏诊或误诊.

Primary immune thrombocytopenia(ITP)is a hematological disease caused by immune-mediated platelet destruction,and it usually presents with skin or mucosal bleeding,while transient global amnesia(TGA)as the initial manifestation of ITP is extremely rare in clinical practice.This article reports one case of ITP with TGA as the initial symp-tom.The patient was an elderly woman without the history of major diseases,and she was admitted due to sudden dizzi-ness and memory disorder.She showed loss of recent memory and asked the same questions repeatedly.Head magnetic resonance imaging showed lacunar infarction in the basal ganglia,and laboratory tests after admission showed a significant reduction in platelet count.The patient was diagnosed with ITP after related examinations and showed improvements in symptoms after standard treatment,without similar episodes thereafter.This case shows that TGA can be a rare initial manifestation of ITP,and for patients with sudden memory disorder in clinical practice,blood abnormalities should be screened to avoid missed diagnosis or misdiagnosis.

钟家俊;张鹏飞;黄崇博;罗梓萌;庞晓宇;李春光

南方医科大学第二临床医学院,广东 广州 510280南方医科大学第二临床医学院,广东 广州 510280南方医科大学第二临床医学院,广东 广州 510280南方医科大学第二临床医学院,广东 广州 510280南方医科大学第二临床医学院,广东 广州 510280南方医科大学第二临床医学院,广东 广州 510280||南方医科大学珠江医院神经内科,广东 广州 510280

医药卫生

原发性免疫性血小板减少症短暂性全面性遗忘症诊断

Primary immune thrombocytopeniaTransient global amnesiaDiagnosis

《中风与神经疾病杂志》 2026 (6)

563-566,4

10.19845/j.cnki.zfysjjbzz.2026.0097

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