利多卡因联合罗哌卡因给药方式对臂丛神经阻滞的影响OA
Effects of Different Administration Methods of Lidocaine Combined with Ropivacaine on Brachial Plexus Block
目的 分析利多卡因联合罗哌卡因混合给药与分开给药对臂丛神经阻滞的影响效果.方法 回顾性纳入 90 例2022 年 6 月至 2025 年 7 月在郑州市第一人民医院接受超声引导下臂丛神经阻滞的上肢手术患者,按照局麻药给药方式分为混合组(47 例)与顺序分次注射组(43 例).比较两组的感觉与运动阻滞起效时间、阻滞后 10 min 与 30 min 完全阻滞率、术后 0、6、12、24 h 的疼痛评分(NRS),以及术中不同时间点心率(HR)与平均动脉压(MAP).同时记录术后并发症发生情况.结果 顺序分次注射组的感觉阻滞与运动阻滞起效时间均短于混合组(P<0.05).顺序分次注射组在 10 min 时感觉、运动完全阻滞率均高于混合组(P<0.05),而 30 min 时两组差异不显著(P>0.05).两组术后各时间点 NRS 评分、术中不同时间点 HR 和 MAP 差异均无统计学意义(P>0.05).两组术后并发症发生率低且差异不显著(P>0.05).结论 利多卡因联合罗哌卡因的分次注射较混合注射可缩短臂丛神经阻滞的起效时间,提升早期(10 min)的完全阻滞率,但对最终(30 min)的完全阻滞率、术后镇痛效果及术中血流动力学影响无显著差异.
Objective To analyze the effects of mixed administration versus separate administration of lidocaine combined with ropivacaine on brachial plexus block.Methods A total of 90 patients who underwent upper-limb surgery under ultrasound-guided brachial plexus block at Zhengzhou First People's Hospital from June 2022 to July 2025 were retrospectively enrolled.According to the method of local anesthetic administration,the patients were divided into a mixed-administration group(47 cases)and a sequential fractional-injection group(43 cases).The onset times of sensory and motor block,the rates of complete sensory and motor block at 10 min and 30 min after blockade,pain scores assessed using the numeric rating scale(NRS)at 0,6,12,and 24 h after surgery,and heart rate(HR)and mean arterial pressure(MAP)at different intraoperative time points were compared between the two groups.Postoperative complications were also recorded.Results The onset times of both sensory block and motor block were shorter in the sequential fractional-injection group than in the mixed-administration group(P<0.05).At 10 min after blockade,the rates of complete sensory and motor block were higher in the sequential fractional-injection group than in the mixed-administration group(P<0.05),whereas no significant differences were observed between the two groups at 30 min(P>0.05).There were no statistically significant differences between the two groups in NRS scores at any postoperative time point or in HR and MAP at different intraoperative time points(P>0.05).The incidence of postoperative complications was low in both groups,with no significant difference between them(P>0.05).Conclusion Compared with mixed injection,fractional injection of lidocaine combined with ropivacaine can significantly shorten the onset time of brachial plexus block and improve the early(10 min)complete block rate,but it has no significant effect on the final(30 min)complete block rate,postoperative analgesic efficacy,or intraoperative hemodynamics.
许少华;金冉
郑州市第一人民医院 麻醉科,河南 郑州 450000郑州市第一人民医院 麻醉科,河南 郑州 450000
臂丛神经阻滞利多卡因罗哌卡因给药方式
brachial plexus blocklidocaineropivacaineadministration method
《临床研究》 2026 (6)
97-100,4
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