泌尿外科患者术后血栓形成危险因素的Meta分析OA
Risk factors for postoperative thrombosis in patients undergoing urological surgery:a Meta-analysis
目的 系统评价泌尿外科患者术后血栓发生率和危险因素.方法 计算机检索PubMed、Embase、The Cochrane Library、Web of Science、中国知网、万方、维普数据库,搜集关于泌尿外科患者术后血栓形成危险因素的研究,检索时限均为建库至2025年5月1日.由2位研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Stata 18.0和RevMan 5.4软件进行Meta分析.结果 共纳入15项研究,包括91 097例患者.Meta分析结果显示,术后血栓发生率为8.2%[95%CI(6.3%,10.1%)];静脉血栓栓塞病史[OR=4.45,95%CI(2.16,9.14),P<0.001]、高血压病史[OR=1.20,95%CI(1.04,1.38),P=0.010]、糖尿病病史[OR=1.71,95%CI(1.01,2.87),P=0.044]、高Caprini评分[OR=1.73,95%CI(1.44,2.08),P<0.001]、高龄[OR=1.37,95%CI(1.14,1.65),P=0.001]、高BMI[OR=1.11,95%CI(1.03,1.20),P=0.009]是泌尿外科患者术后血栓形成的危险因素.结论 临床实践中应重点关注术后血栓形成的危险因素并对患者进行评估,对存在高危因素的患者制定个体化预防策略,加强围手术期风险评估与干预,以降低术后血栓发生率,改善患者预后.
Objective To systematically evaluate the incidence and risk factors of postoperative thrombosis in patients undergoing urological surgery.Methods PubMed,Embase,The Cochrane Library,Web of Science,CNKI,WanFang Data and VIP databases were electronically searched to collect studies on risk factors of postoperative thrombosis in urological patients from inception to May 1,2025.Two reviewers independently screened literature,extracted data and assessed the risk of bias of the included studies.Meta-analysis was conducted using Stata 18.0 and RevMan 5.4 software.Results A total of 15 studies involving 91,097 patients were included.The Meta-analysis results showed that the incidence of postoperative thrombosis was 8.2%[95%CI(6.3%,10.1%)];history of venous thromboembolism[OR=4.45,95%CI(2.16,9.14),P<0.001],history of hypertension[OR=1.20,95%CI(1.04,1.38),P=0.010],history of diabetes[OR=1.71,95%CI(1.01,2.87),P=0.044],high Caprini score[OR=1.73,95%CI(1.44,2.08),P<0.001],advanced age[OR=1.37,95%CI(1.14,1.65),P=0.001],and high BMI[OR=1.11,95%CI(1.03,1.20),P=0.009]were risk factors for postoperative thrombosis.Conclusion In clinical practice,it is necessary to pay attention to the above risk factors of postoperative thrombosis and evaluate patients.For patients with high-risk factors,individualized prevention strategies should be formulated,and perioperative risk assessment and intervention should be strengthened to reduce the incidence of postoperative thrombosis and improve the prognosis of patients.
杨刚;卢童;杨军;万涛;熊标;罗帆;周治军
武汉科技大学附属天门医院/天门市第一人民医院泌尿外科(湖北天门 431700)武汉科技大学附属天门医院/天门市第一人民医院泌尿外科(湖北天门 431700)||武汉科技大学职业危害识别与控制湖北省重点实验室(武汉 430000)武汉科技大学附属天门医院/天门市第一人民医院泌尿外科(湖北天门 431700)武汉科技大学附属天门医院/天门市第一人民医院泌尿外科(湖北天门 431700)武汉科技大学附属天门医院/天门市第一人民医院泌尿外科(湖北天门 431700)武汉科技大学附属天门医院/天门市第一人民医院泌尿外科(湖北天门 431700)武汉科技大学附属天门医院/天门市第一人民医院泌尿外科(湖北天门 431700)
医药卫生
泌尿外科血栓危险因素Meta分析
UrologyThrombosisRisk factorsMeta-analysis
《医学新知》 2026 (6)
679-685,中插14-中插15,9
职业危害识别与控制湖北省重点实验室开放基金项目(JF2024-G23)
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