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枸杞子对少弱精子症干预的应用研究OA

Applied research on the intervention of Gouqizi(Lycii Fructus)in oligoasthenozoospermia

中文摘要英文摘要

男性不育症中的少弱精子症已成为重要的生殖健康问题,药食同源理念为男性生殖的长期调理提供了安全有效的策略.枸杞子作为典型的药食同源药材,目前在中医不育症诊疗中被广泛应用.枸杞子中的多种核心成分可通过抗氧化应激、调节下丘脑-垂体-性腺轴功能等途径,保护生精细胞、提升精子质量,与少弱精子症的发病病机充分契合.枸杞子复方能显著改善少弱精子症患者的精液指标与生殖功能,结合不同证型的枸杞药膳方案适合长期进行干预.深入开展枸杞子改善少弱精子症的应用研究,既符合"未病先防"的理念,也具有重要的临床价值,为应对男性生育力下降挑战提供了低成本、高接受度的干预策略.

Oligoasthenozoospermia,a major contributor to male infertility,has emerged as a significant reproductive health concern.The concept of food-medicine homology offers a safe and effective strategy for the long-term management of male reproductive function and is currently widely applied in the diagnosis and treatment of infertility in Chinese medicine.Various bioactive components in Gouqizi(Lycii Fructus)can protect spermatogenic cells and improve sperm quality through mechanisms such as anti-oxidative stress and regulation of the hypothalamic-pituitary-gonadal axis,which closely correspond to the pathogenesis of oligoasthenozoospermia.Compound formulas containing Gouqizi(Lycii Fructus)have been shown to significantly improve semen parameters and reproductive function in patients with oligoasthenozoospermia,and medicated diet regimens tailored to different TCM patterns are suitable for long-term intervention.In-depth applied research on Gouqizi(Lycii Fructus)in ameliorating oligoasthenozoospermia not only aligns with the TCM principle of"preventing a disease before it arises,"but also holds substantial clinical value,providing a low-cost,highly acceptable intervention strategy to address the declining trend in male fertility.

庄啸;张成;曾小珂;何清湖

湖南中医药大学中西医结合学院,湖南长沙 410208湖南中医药大学中西医结合学院,湖南长沙 410208湖南医药学院,湖南怀化 418000湖南中医药大学中西医结合学院,湖南长沙 410208

医药卫生

药食同源枸杞子少弱精子症生殖健康抗氧化

food-medicine homologyGouqizi(Lycii Fructus)oligoasthenozoospermiareproductive healthantioxidation

《药食同源杂志》 2026 (6)

452-460,9

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