可视化角膜生物力学分析仪在眼科中的应用OA
Application of corneal visualization scheimpflug technology in ophthalmology
可视化角膜生物力学分析仪(corneal visualization scheimpflug technology,Corvis ST)结合超高速Scheimpflug 成像与非接触式眼压测量技术,能够动态监测角膜形变和恢复过程,提供最大凹陷(highest concavity,HC)、曲率半径参数(radius,R)、应力-应变指数(stress-strain index,SSI)、第一次压平硬度参数(stiffness parameter at the first applanation,SP-A1)和最大凹陷硬度参数(stiffness parameter at the highest concavity,SP-HC)等多项关键生物力学参数.这些功能有助于眼科疾病的诊断和治疗.该设备在圆锥角膜的早期筛查与评估、屈光手术的术前筛查与术后监测、青光眼分型及视神经监测中具有重要价值.此外,Corvis ST 还可用于甲状腺相关眼病、糖尿病性视网膜病变、中心性浆液性脉络膜视网膜病变等多种眼部疾病的生物力学特征分析,并为非感染性葡萄膜炎、遗传性视网膜病变等系统性疾病的角膜并发症提供早期预警.本文系统综述了 Corvis ST 的测量原理、关键参数及最新临床应用进展,旨在为眼科疾病的诊治提供支持.
The Corneal Visualization Scheimpflug Technology(Corvis ST)combines ultra-high-speed Scheimpflug imaging with non-contact tonometry,allowing for dynamic monitoring of the corneal deformation and recovery process.It provides a range of key biomechanical parameters,including highest concavity(HC),radius of curvature(R),stress-strain index(SSI),stiffness parameter at first applanation(SP-A1),and stiffness parameter at highest concavity(SP-HC).The system holds particular clinical value in the early screening and assessment of keratoconus,preoperative screening and postoperative monitoring in refractive surgery,as well as glaucoma classification and optic nerve evaluation.In addition to these applications,it aids in the biomechanical characterization of various ocular pathologies,such as thyroid-associated ophthalmopathy,diabetic retinopathy,and central serous chorioretinopathy,and serves as an early warning system for corneal complications in systemic disorders like non-infectious uveitis and inherited retinal diseases.This systematic review provides a comprehensive examination of the measurement principles,key parameters,and recent clinical advancements related to Corvis ST,with the ultimate aim of supporting its diagnostic and therapeutic application in ophthalmic practice.
崔金利;蔡晨希;刘泽浩;刘欣雨;冷云霞;林英
中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060首都医科大学北京电力教学医院,北京 100073中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060华南理工大学附属第一医院/广州市第一人民医院眼科,广州 510180中山大学中山眼科中心,眼病防治全国重点实验室,广东省眼科视觉科学重点实验室,广州 510060
医药卫生
角膜巩膜生物力学可视化角膜生物力学分析仪
corneasclerabiomechanicsCorvis ST
《眼科学报》 2026 (5)
404-415,12
广州市科技计划项目(SL2022A03J00452)广东省本科教育高等教学质量与教学改革工程建设项目(粤教高函[2024]9 号)中山大学 2023 年校级本科教学质量工程项目(教务 2023-394-39)白求恩·朗沐中青年眼科科研基金(BJ-LM2021014J)2024 年度眼科新技术孵化基金.This work was supported by the Science and Technology Program of Guangzhou,China(SL2022A03J00452)Higher Education Quality and Teaching Reform Construction Project for Undergraduate Education in Guangdong Province,China([2024]9)Sun Yat-sen University's 2023 University-level Undergraduate Teaching Quality Engineering Project,China(2023-394-39)the Bethune·Lumitin Research Funding for the young and middle-aged Ophthalmologists,China(BJ-LM2021014J)and Ophthalmology New Technology Incubation Fund.
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