湖羊布鲁氏菌病防控技术研究进展OA

Brucellosis is a zoonotic disease that severely endangers the Hu sheep industry,posing multiple challenges to agri-cultural production,public health security and animal welfare worldwide.This article outlines the epidemiological characteristics of brucellosis and its specific impacts on Hu sheep breeding,systematically sorts out the application status,advantages and dis-advantages of serological detection(Rose Bengal Plate Test,Standard Agglutination Test,etc.)and molecular biological detec-tion(real-time fluorescent PCR,whole-genome sequencing,etc.)technologies,details the research and development progress of attenuated live vaccines,inactivated vaccines,subunit vaccines and DNA vaccines,and emphasizes the core value of establishing a biosafety system.It summarizes the core achievements and practical limitations of current prevention and control technologies,analyzes the main challenges in technical application and management practice,and puts forward targeted countermeasures and future research directions,providing scientific reference for the precise prevention and control of brucellosis in Hu sheep.