类固醇激素与自体骨髓注射结合弹性髓内针治疗儿童长骨单纯性骨囊肿的临床对照研究OA
Comparative Clinical Study of Corticosteroid versus Autologous Bone Marrow Injection Combined with Elastic Stable Intramedullary Nailing for Pediatric Long-Bone Unicameral Bone Cyst
目的 比较弹性髓内针(ESIN)分别联合类固醇激素与自体骨髓(ABM)注射治疗儿童长骨单纯性骨囊肿(UBC)的疗效与安全性.方法 回顾性分析2015-01 至2023-12 解放军总医院第一医学中心和第七医学中心收治的 UBC 患儿 45 例,分为 A 组(21 例,ESIN+类固醇激素)和 B 组(24 例,ESIN+ABM).术后定期行影像学随访,依据 Capanna 标准评估囊肿愈合情况.结果 45 例均获随访,平均随访 40.4 个月.A 组总有效率为 90.5%(19/21),B 组总有效率为 91.7%(22/24),两组差异无统计学意义(P=0.89).45 例中,治愈 28 例(62.2%),部分愈合 13 例(28.9%),复发 2 例(4.4%),治疗无效2 例(4.4%).结论 ESIN 分别联合类固醇激素与 ABM 注射均是治疗 UBC 安全有效的微创方法.
Objective To compare the efficacy and safety of elastic stable intramedullary nailing(ESIN)combined with corti-costeroid versus combined with autologous bone marrow(ABM)injection in the treatment of unicameral bone cyst(UBC)in the long bones of children.Methods A retrospective analysis was performed on 45 children with UBC admitted to the First and the Seventh Medical Centers of the PLA General Hospital from January 2015 to December 2023.The patients were divided into group A(n=21,ESIN plus corticosteroid)and group B(n=24,ESIN plus ABM injection).Postoperative imaging follow-up was performed regularly,and cyst healing was evaluated according to the Capanna criteria.Results All the 45 patients completed follow-up,with a mean follow-up duration of 40.4 months.The overall effective rate was 90.5%(19/21)in group A and 91.7%(22/24)in group B,with no sta-tistically significant difference between the two groups(P=0.89).Among the 45 cases,28(62.2%)achieved complete healing,13(28.9%)had partial healing,2(4.4%)developed recurrence,and 2(4.4%)showed no response to treatment.Conclusions Both ESIN combined with corticosteroid and ESIN combined with ABM injection are safe and effective minimally inva-sive methods for the treatment of UBC.
杜英杰;姚佳岐;刘丽;邓湘玲;李文超
100853 北京,解放军医学院100853 北京,解放军医学院100700 北京,解放军总医院第七医学中心儿科医学部100700 北京,解放军总医院第七医学中心儿科医学部100700 北京,解放军总医院第七医学中心儿科医学部
医药卫生
单纯性骨囊肿儿童弹性髓内针类固醇激素自体骨髓血
unicameral bone cystchildrenelastic intramedullary nailingcorticosteroidautologous bone marrow
《武警医学》 2026 (6)
491-496,505,7
军队某课题资助,北京市自然科学基金(7192196)
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