助孕女性体力活动水平与IVF/ICSI治疗后妊娠率相关性Meta分析OA

Objectives:To systematically evaluate the correlation between physical activity and pregnancy rate of in vitro fertilization(IVF)or intracytoplasmic sperm injection(ICSI)in women undergoing assisted reproduction. Methods:Databases including PubMed,Embase,Wanfang,VIP and the China National Knowledge Infrastructure(CNKI)were searched to collect cohort studies on the association between physical activity and pregnancy rate of IVF/ICSI from inception of the database to May 1,2025.Three reviewers independently screened literature,extracted data,and assessed study quality.Meta-analysis was performed using Stata 10.0 software. Results:Eight articles involving 1 927 participants were included.The meta-analysis showed that compared to women undergoing fertility treatment with low physical activity levels,those with moderate physical activity levels demonstrated a higher pregnancy rate in IVF/ICSI treatment[OR=1.36,95％CI(1.13,1.63),P＜0.05].Subgroup analyses based on data sources,follow-up time,and ART types indicated that physical activity remained a significant factor influencing pregnancy rates(P＜0.05).Sensitivity analysis confirmed the stability of the results.The funnel plot was symmetrical,and the results of the Egger's test and the Begg's test suggested no publication bias(P＞0.05). Conclusions:Moderate physical activity can improve pregnancy rates in women undergoing IVF/ICSI treatment.It is suggested that this population maintain appropriate activity frequency and intensity before treatment.