家庭护士食疗理论在超重和肥胖围绝经期综合征病人中的实证研究OA
Empirical study of the family nurse dietary therapy theory in overweight and obese patients with perimenopausal syndrome
目的:观察基于家庭护士食疗理论构建的家庭护士食疗方案改善超重和肥胖围绝经期病人更年期症状严重程度、代谢指标、氧化应激水平的有效性.方法:于2025年5月25日—8月29日,选取在山西省某三级甲等医院妇科门诊及某社区卫生服务中心招募的70例超重和肥胖围绝经期综合征病人作为研究对象,将病人随机分为对照组和干预组,每组35例.对照组实施常规饮食方案,干预组在常规护理基础上采用家庭护士食疗方案.于干预前及干预6周后评价病人的人体测量学指标、血生化指标、炎症指标、氧化应激指标.结果:干预期间脱落8例病人,最终两组各31例病人完成试验.干预组干预6周后,体重、体质指数(BMI)、腰围、腹围、臀围、体脂肪量、内脏脂肪面积、空腹血糖(FPG)、空腹胰岛素(FINS)、胰岛素抵抗指数(HOMA-IR)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、同型半胱氨酸(Hcy)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、血尿素氮(BUN)、血肌酐(Scr)、血清尿酸(UA)、肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、丙二醛(MDA)水平低于干预前,且BMI、腹围、臀围、体脂肪量、FPG、HOMA-IR、TG、LDL-C、Hcy、TNF-α、hs-CRP、IL-6、MDA小于同期对照组;超氧化物歧化酶(SOD)高于干预前及同期对照组(均P<0.05).结论:富含非营养素的家庭护士食疗方案可以缓解超重和肥胖围绝经期综合征病人更年期症状,有效改善病人人体成分、糖脂代谢水平、炎症氧化应激水平.
Objective:To observe the effectiveness of a family nurse dietary therapy regimen,developed based on the family nurse dietary therapy theory,in improving the severity of menopausal symptoms,metabolic indicators,and oxidative stress levels in overweight and obese patients with perimenopausal syndrome.Methods:A total of 70 overweight and obese patients with perimenopausal syndrome were selected as study subjects from the gynecology outpatient clinic of a tertiary grade A hospital and a resident community in Shanxi province from May 25,2025 to August 29,2025.Patients were randomly divided into control group and intervention group,35 cases each.The control group patients received a conventional dietary program,while the intervention group cases received the family nurse dietary therapy regimen in addition to routine care.Anthropometric indicators,blood biochemical indicators,inflammatory indicators,and oxidative stress indicators were evaluated before the intervention and 6 weeks after the intervention.Results:During the intervention period,8 cases dropped out,31 patients in each group completed the trial.After 6 weeks of intervention,the intervention group demonstrated significantly lower levels than those before the intervention in terms of body weight,body mass index(BMI),waist circumference,abdominal circumference,hip circumference,body fat mass,visceral fat area,fasting plasma glucose(FPG),fasting insulin(FINS),homeostatic model assessment for insulin resistance(HOMA-IR),total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),homocysteine(Hcy),alanine aminotransferase(ALT),aspartate aminotransferase(AST),blood urea nitrogen(BUN),serum creatinine(Scr),serum uric acid(UA),tumor necrosis factor-alpha(TNF-α),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6),and malondialdehyde(MDA).Furthermore,the BMI,abdominal circumference,hip circumference,body fat mass,FPG,HOMA-IR,TG,LDL-C,Hcy,TNF-α,hs-CRP,IL-6,and MDA were significantly lower in the intervention group than that in the control group at the same time.Superoxide dismutase(SOD)levels were higher in the intervention group than that before the intervention.The SOD was significantly higher in the intervention group that in the control group at the same time(P<0.05).Conclusions:The family nurse dietary therapy regimen,rich in non-nutrients,alleviated menopausal symptoms and effectively improved body composition,glucose and lipid metabolism,and inflammatory and oxidative stress levels in overweight and obese patients with perimenopausal syndrome.
凌璇;张欢;韩世范;闫蕊;马辰婧;刘洽;吕嘉玲;李馨煜;赵奕雯;张珺
山西医科大学护理学院,山西 030001山西全能家庭护士医药科技有限公司山西医科大学护理学院,山西 030001||山西医科大学食疗科技研究中心||山西省食疗和农产品处方产业技术创新战略联盟||山西省大健康产教融合重大平台载体与实训基地||山西医科大学第一医院山西医科大学护理学院,山西 030001山西医科大学医学科学院山西医科大学护理学院,山西 030001山西医科大学护理学院,山西 030001山西医科大学医学科学院山西医学期刊社有限责任公司山西医科大学护理学院,山西 030001
家庭护士食疗理论超重肥胖围绝经期综合征非营养素饮食干预
family nurse dietary therapy theoryoverweightobesityperimenopausal syndromenon-nutrientsdietary intervention
《护理研究》 2026 (14)
2385-2392,8
2023-2024年度山西省大健康产业高质量发展科研专项项目,编号:DJKZXKT2023002山西省食疗和农产品处方产业技术创新战略联盟项目
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