Enrichment and amplification of secreted α-synuclein from cellular model and saliva of patients with synucleinopathiesOA
Enrichment and amplification of secreted α-synuclein from cellular model and saliva of patients with synucleinopathies
Wuxian Xu;Mingyue Luan;Zhaoxia Wang;Jianwen Deng;Li Zhu
Sino-Danish College,University of Chinese Academy of Sciences,Beijing 100049,China||State Key Laboratory of Cognitive Science and Mental Health,Institute of Biophysics,Chinese Academy of Sci-ences,Beijing 100101,ChinaDepartment of Neurology,Peking University First Hospital,Beijing 100034,ChinaDepartment of Neurology,Peking University First Hospital,Beijing 100034,ChinaDepartment of Neurology,Peking University First Hospital,Beijing 100034,ChinaSino-Danish College,University of Chinese Academy of Sciences,Beijing 100049,China||State Key Laboratory of Cognitive Science and Mental Health,Institute of Biophysics,Chinese Academy of Sci-ences,Beijing 100101,China||College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China
α-SynucleinParkinson's diseaseSeeding activityRT-QuICSaliva biomarkersSynucleinopathies
α-SynucleinParkinson's diseaseSeeding activityRT-QuICSaliva biomarkersSynucleinopathies
《生物物理学报（英文）》 2026 (3)
137-150,14
This work was supported by the National Natural Science Foundation of China(32271200),the Capitals Funds for Health Improvement and Research(2022-4-40716),and the National Key Research and Development Program of China(2019YFA0508603).We are indebted to the cooperation of the patients and their families.Figures are created at https://BioRender.com.
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