火针联合针刺治疗胃食管反流病的疗效观察OA
Observation on the efficacy of fire needling plus acupuncture for gastroesophageal reflux disease
目的 观察贺氏火针联合针刺治疗中虚气逆型胃食管反流病的临床疗效.方法 将纳入的76 例胃食管反流病患者随机分为观察组和对照组,每组38 例.观察组予贺氏火针联合针刺治疗,对照组予单纯针刺治疗.比较两组临床疗效和复发率,观察两组治疗前后反流性疾病问卷(reflux disease questionnaire,RDQ)、胃食管反流病相关生存质量量表(gastroesophageal reflux disease-health related quality of life,GERD-HRQL)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)和匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)的评分变化,观察两组治疗前后血清5-羟色胺(5?hydroxytryptamine,5-HT)、γ-氨基丁酸(γ-aminobutyric acid,GABA)和血管活性肠肽(vasoactive intestinal peptide,VIP)的水平变化.结果 治疗后,两组RDQ、HAMA、GERD-HRQL和PSQI 评分均较治疗前降低(P<0.05),且观察组上述评分均优于对照组(P<0.05).治疗后,两组血清 5-HT 和 GABA 水平较治疗前升高(P<0.05),VIP 水平较治疗前降低(P<0.05);且观察组 5-HT 和GABA 水平高于对照组(P<0.05),VIP 水平低于对照组(P<0.05).观察组总有效率为 94.3%,高于对照组的85.3%,但组间比较差异无统计学意义(P>0.05).观察组复发率为13.3%,低于对照组的 42.1%,差异有统计学意义(P<0.05).结论 贺氏火针联合针刺治疗中虚气逆型胃食管反流病可缓解临床症状,改善患者生活质量、睡眠质量和焦虑程度,降低胃食管反流病的复发率.
Objective To observe the clinical efficacy of He's fire needling for gastroesophageal reflux disease of middle Jiao deficiency and Qi adverse rising type.Method Seventy-six included patients with gastroesophageal reflux disease were randomized to an observation group and a control group,with 38 cases in each group.The observation group received He's fire needling plus acupuncture and the control group received acupuncture alone.The clinical therapeutic effects and recurrence rates were compared between the two groups.The reflux disease questionnaire(RDQ),the gastroesophageal reflux disease-health related quality of life(GERD-HRQL)questionnaire,Hamilton anxiety scale(HAMA)and Pittsburgh sleep quality index(PSQI)scores were recorded in the two groups before and after treatment.Serum 5-hydroxytryptamine(5-HT),γ-aminobutyric acid(GABA)and vasoactive intestinal peptide(VIP)levels were measured in the two groups before and after treatment.Result After treatment,the RDQ,HAMA,GERD-HRQL and PSQI scores decreased in the two groups compared with before(P<0.05)and were lower in the observation group than in the control group(P<0.05).After treatment,serum 5-HT and GABA levels increased(P<0.05)and VIP levels decreased(P<0.05)in the two groups compared with before;5-HT and GABA levels were higher(P<0.05)and VIP levels were lower(P<0.05)in the observation group than in the control group(P<0.05).The total efficacy rate was 94.2%in the observation group,which was higher than 85.3%in the control group,but there was no statistically significant between-group difference(P>0.05).The recurrence rate was 13.3%in the observation group,which was lower than 42.1%in the control group with a statistically significant difference(P<0.05).Conclusion He's fire needling plus acupuncture can relieve the clinical symptoms,improve the patients'quality of life and sleep,reduce the severity of anxiety and decrease the recurrence rate in treating gastroesophageal reflux disease of middle Jiao deficiency and Qi adverse rising type.
姚金;张媛;洪秋阳;邓越;曾沁;张丽;周素芳
北京中医医院顺义医院,北京 101300北京中医医院顺义医院,北京 101300北京中医医院顺义医院,北京 101300北京中医医院顺义医院,北京 101300北京中医医院顺义医院,北京 101300北京中医医院顺义医院,北京 101300贵州中医药大学第一附属医院,贵阳 550001
医药卫生
针刺疗法火针疗法胃食管反流病焦虑生活质量睡眠质量
Acupuncture therapyFire-needle therapyGastroesophageal reflux diseaseAnxietyQuality of lifeSleep quality
《上海针灸杂志》 2026 (6)
622-628,7
国家中医药管理局第五批全国中医临床优秀人才研修项目[国中医药人教函(2022)1号]北京市中医管理局专项资助项目(QN2016-12)国家自然科学基金青年项目(82104816)
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