从"气-血-冲任"论治围绝经期崩漏OA
Treatment of perimenopausal metrorrhagia from the perspective of"Qi-blood-chong and ren meridians"
基于"气-血-冲任"理论体系,探讨围绝经期崩漏的发病机制及分期治疗方案,为临床提供理论依据和实践指导.围绝经期崩漏是妇科常见内分泌紊乱性疾病,其核心病机在于肾气渐衰导致气血亏虚、冲任失调,临床表现为经血非时而下.研究提出三期辨治方案:暴崩期以"益气固脱、塞流止血"为要,方用加味四物汤(四物汤加生地黄、地骨皮)止血养血;漏下期重在"健脾益气、澄源复旧",予归脾汤调和气血;调养期固本则侧重"补肾填精、调理冲任",选用二仙汤合六味地黄丸平衡阴阳.加味四物汤中生地黄、地骨皮可通过调节凝血-纤溶系统、改善子宫内膜微环境等途径发挥止血作用,归脾汤能有效调节下丘脑-垂体-卵巢轴功能,而二仙汤合六味地黄丸则通过调控雌激素水平而改善冲任.分期治疗体现"治血先调气,固冲必补肾"思想,为临床提供传统中医理论与现代医学依据兼具的诊疗思路.
Based on the theoretical framework of"Qi-blood-chong and ren meridians",this paper explores the patho-genesis and stage-based treatment strategies for perimenopausal metrorrhagia,aiming to provide theoretical basis and prac-tical guidance for clinical practice.Perimenopausal metrorrhagia is a common endocrine disorder in gynecology.Its core pathogenesis lies in the gradual decline of kidney-Qi,leading to deficiency of both Qi and blood,as well as imbalance of the Cchong and ren meridians,clinically manifested as untimely uterine bleeding.This study proposes a three-stage treatment approach:in the acute profuse bleeding stage,the priority is to"supplement Qi to prevent collapse,and stop bleeding by blocking the flow",for which modified Siwu Decoction(Siwu Decoction plus Shengdihuang and Digupi)is used to stop bleed-ing and nourish blood.In the continuous spotting stage,the focus is on"invigorating the spleen and supplementing Qi,clear-ing the source and restoring normal function",with Guipi Decoction applied to harmonize Qi and blood.In the recuperation stage,the emphasis is on"tonifying the kidney and replenishing essence,regulating the chong and ren meridians",using Erxian Decoction combined with Liuwei Dihuang Pill to balance Yin and Yang.In modified Siwu Decoction,Shengdihuang and Digupi exert hemostatic effects by regulating the coagulation-fibrinolysis system and improving the endometrial micro-environment.Guipi Decoction effectively regulates the hypothalamic-pituitary-ovarian axis function.Meanwhile,Erxian De-coction combined with Liuwei Dihuang Pill modulates estrogen levels,thereby regulating the chong and ren meridians.This stage-based treatment embodies the principle of"regulating Qi before treating bleeding,and tonifying the kidney to stabilize the chong meridian",offering diagnosis and treatment ideas that integrate traditional Chinese medicine theory with modern medical evidence.
李柳洁;郭晓辉;李让钱;刘照峰
山西省中医药研究院,山西 太原 030012山西中医药大学,山西 晋中 030619山西省针灸医院,山西 太原 030012山西省针灸医院,山西 太原 030012
医药卫生
围绝经期崩漏气-血-冲任止血
perimenopausal metrorrhagiaQi-blood-chong and ren meridianshemostasis
《山西中医药大学学报》 2026 (6)
691-695,5
山西省中医药管理局中医药创新团队项目(zyytd2024014)
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