蒙药那仁满都拉及其配伍单药多糖铁的含铁量与性质分析OA

Using the Mongolian medicine Narenmandula and its 11 compatible single drugs as raw materials,poly-saccharides were extracted and 12 kinds of polysaccharide iron were prepared respectively,and qualitative and quanti-tative analyses were conducted on them.The formation of iron cores was characterized by infrared spectroscopy(IR),the iron content was determined by micro-indirect iodometric method,and the water solubility,stability,and reducibil-ity were examined by chemical analysis methods.The results showed that 12 polysaccharides formed Fe-OOH iron cores with Fe³+,exhibiting a polymeric β-Fe-OOH structure.All 12 polysaccharide iron complexes were amorphous powdery solids with good water solubility and stability.They could dissociate Fe³+ in acidic medium and could be re-duced by ascorbic acid(VC)in approximately 5 h.Their iron content ranged from 20.56%to 45.50%.These findings indicate that the 12 polysaccharides formed stable water-soluble complexes with Fe³+,which could be completely re-duced under the action of VC,and had good bioavailability.