银纳米改性口腔修复材料的抗菌性能及生物安全性挑战OA

Oral bacterial infections serve as primary etiological factors for dental caries and periodontal diseases.Conventional restorative materials,due to their lack of active antimicrobial properties,often lead to secondary caries and peri-implantitis.Silver nanoparticles exhibit broad-spectrum antimicrobial activity,sus-tained-release properties and low resistance induction,demonstrating significant potential for enhancing the antibacterial performance of materials.This review summarized the modification strategies,antibacterial mechanisms and biosafety challenges associated with silver nanoparticles in both dental implant restorative materials and resin restorative materials,aiming to provide a reference for developing novel restorative materi-als that integrate effective antibacterial properties with biosafety.