首页|期刊导航|河北中医|柴胡疏肝散加减联合调神针刺法治疗产后抑郁效果观察

柴胡疏肝散加减联合调神针刺法治疗产后抑郁效果观察OA

Effect of modified Chaihu Shugan Powder combined with the Tiaoshen acupuncture method in the treatment of postpartum depression

中文摘要英文摘要

目的 探究柴胡疏肝散加减联合调神针刺法治疗产后抑郁的疗效.方法 选取 2022 年 2 月至 2024 年 1月徐州市中心医院妇产科收治的 94 例产后抑郁患者,按随机数字表法分为治疗组和对照组,每组 47 例.2 组均予以对症治疗,对照组加调神针刺法治疗,治疗组在对照组基础上联合柴胡疏肝散加减治疗,连续治疗 4 周.比较 2 组临床疗效、不良反应及治疗前后中医证候积分、爱丁堡产后抑郁量表(EPDS)、汉密尔顿抑郁量表(HAMD)评分及雌二醇、孕酮水平.结果 治疗组总有效率为 97.87%(46/47),对照组总有效率为 82.98%(39/47),治疗组总有效率明显高于对照组(P<0.05).治疗后,2 组多思善虑、精神不振、失眠多梦、悲伤欲哭评分及 EPDS、HAMD 评分均低于治疗前(P<0.05),且治疗组明显低于对照组(P<0.05).治疗后,2 组雌二醇水平均升高(P<0.05),且治疗组明显高于对照组(P<0.05);治疗后,2 组孕酮水平均降低(P<0.05),且治疗组明显低于对照组(P<0.05).治疗组不良反应发生率为 4.26%(2/47),对照组为 6.38%(3/47),2 组不良反应发生率比较差异无统计学意义(P>0.05).结论 柴胡疏肝散加减联合调神针刺法治疗产后抑郁疗效显著,可有效缓解患者多思善虑等症状,减轻抑郁病情,调节雌激素和孕激素,安全有效.

Objective To investigate the efficacy of modified Chaihu Shugan Powder combined with the Tiaoshen acupuncture method in the treatment of postpartum depression.Methods A total of 94 patients with postpartum depression admitted to the Department of Obstetrics and Gynecology of Xuzhou Central Hospital from February 2022 to January 2024 were selected and randomly assigned to a treatment group and a control group,with 47 patients in each group.Both groups received symptomatic treatment.The control group received additional Tiaoshen acupuncture,while the treatment group received modified Chaihu Shugan Powder in combination with Tiaoshen acupuncture on the basis of the control group.Treatment was continued for 4 weeks.Clinical efficacy,adverse reactions,traditional Chinese medicine(TCM)syndrome scores,Edinburgh Postnatal Depression Scale(EPDS)scores,Hamilton Depression Scale(HAMD)scores,estradiol levels,and progesterone levels were compared before and after treatment.Results The total effective rate was 97.87%(46/47)in the treatment group and 82.98%(39/47)in the control group,with a significantly higher rate in the treatment group(P<0.05).After treatment,scores for overthinking and worry,low energy,insomnia with dreaming,and sadness with tearfulness,as well as EPDS and HAMD scores,were lower in both groups than before treatment(P<0.05),and were significantly lower in the treatment group than in the control group(P<0.05).After treatment,estradiol levels increased in both groups(P<0.05),with a significantly greater increase in the treatment group(P<0.05);progesterone levels decreased in both groups(P<0.05),with a significantly greater decrease in the treatment group(P<0.05).The incidence of adverse reactions was 4.26%(2/47)in the treatment group and 6.38%(3/47)in the control group,with no statistically significant difference between the two groups(P>0.05).Conclusion Modified Chaihu Shugan Powder combined with the Tiaoshen acupuncture method is effective for postpartum depression.It can relieve symptoms such as overthinking and worry,reduce depressive severity,regulate estrogen and progesterone levels,and is safe and effective.

郭琳琳;汤欣

徐州市中心医院妇产科,江苏 徐州 221000徐州市中心医院妇产科,江苏 徐州 221000

医药卫生

抑郁症,产后柴胡疏肝散针刺疗法调神雌激素

Depression,postpartumChaihu Shugan PowderAcupuncture therapyTiaoshenEstrogen

《河北中医》 2026 (6)

906-909,4

10.3969/j.issn.1002-2619.2026.06.006

评论