首页|期刊导航|感染、炎症、修复|眼科临床中干眼症的综合治疗与生活质量改善研究

眼科临床中干眼症的综合治疗与生活质量改善研究OA

Comprehensive treatment and quality of life improvement of dry eye disease in clinical ophthalmology

中文摘要英文摘要

目的 探讨综合治疗对干眼症患者的临床疗效、视功能相关指标以及生活质量的影响.方法 选取2023年1月至2025年2月于梧州市工人医院门诊就诊的干眼症患者90例,采用随机数表法分为综合治疗组和常规治疗组,每组45例.比较两组临床疗效、视功能、生活质量以及不良反应发生情况.结果 综合治疗组总有效率(95.56%)高于常规治疗组(80.00%;χ2值为10.284,P<0.05).治疗后,两组泪液分泌实验、泪膜破裂时间高于治疗前,且综合治疗组高于常规治疗组(P<0.05);治疗后,两组荧光素染色低于治疗前,且综合治疗组低于常规治疗组(P<0.05).治疗后,两组视觉相关生存质量评分高于治疗前,且综合治疗组高于常规治疗组(P<0.05);治疗后,两组眼表疾病指数评分低于治疗前,且综合治疗组低于常规治疗组(P<0.05).结论 综合治疗干眼症能有效提高临床疗效,改善视功能,提升患者生活质量,值得临床推广应用.

Objective To investigate the impact of comprehensive therapy on clinical efficacy,visual function indices and quality of life in patients with dry eye disease.Methods A total of 90 patients with dry eye disease who attended the Outpatient Department of Wuzhou GongRen Hospital from January 2023 to February 2025 were enrolled.They were divided into a comprehensive treatment group and a conventional treatment group using the random number table method,with 45 cases in each group.The clinical efficacy,visual function,quality of life,and the incidence of adverse reactions were compared between the two groups.Results The overall response rate in the comprehensive treatment group(95.56%)was significantly higher than that in the conventional treatment group(80.00%;χ2=10.284,P<0.05).After treatment,Schirmer I test results and tear film breakup time were significantly higher than those before treatment in both groups,with significantly higher values in the comprehensive treatment group than in the conventional treatment group(P<0.05).After treatment,fluorescein staining scores were significantly lower than those before treatment in both groups,with significantly lower scores in the comprehensive treatment group than in the conventional treatment group(P<0.05).Additionally,the vision-related quality of life scores increased in both groups after treatment and were higher in the comprehensive treatment group(P<0.05).The Ocular Surface Disease Index scores of the two groups declined after treatment,and the comprehensive treatment group had lower scores(P<0.05).Conclusions Comprehensive treatment for dry eye disease can effectively enhance clinical efficacy,improve visual function,and enhance patients'quality of life.It is worthy of clinical promotion and application.

贺玮

梧州市工人医院眼科,广西 梧州 543000

眼科临床干眼症综合治疗生活质量

clinical ophthalmologydry eye diseasecomprehensive treatmentquality of life

《感染、炎症、修复》 2026 (3)

296-300,5

10.3969/j.issn.1672-8521.2026.03.014

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